Sympathetic Innervation Induced in Engrafted Engineered Cardiomyocyte Sheets by Glial Cell Line Derived Neurotrophic Factor In Vivo

The aim of myocardial tissue engineering is to repair or regenerate damaged myocardium with engineered cardiac tissue. However, this strategy has been hampered by lack of functional integration of grafts with native myocardium. Autonomic innervation may be crucial for grafts to function properly wit...

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Veröffentlicht in:	BioMed research international 2013-01, Vol.2013 (2013), p.1-8
Hauptverfasser:	Lee, Jong-Kook, Fu, Xian-ming, Miwa, Keiko, Shimizu, Tatsuya, Takagishi, Yoshiko, Hirabayashi, Masumi, Watabe, Kazuhiko, Usui, Akihiko, Kodama, Itsuo, Ueda, Yuichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviridae Adenovirus Allografts Animals Glial Cell Line-Derived Neurotrophic Factor - genetics Heart Heart - innervation Heart cells Heart Transplantation Humans Myocytes, Cardiac - metabolism Myocytes, Cardiac - transplantation Neuroglia - metabolism Neuroglia - pathology Neurotrophic functions Physiological aspects Postoperative period Rats Rodents Science Sympathetic Nervous System - growth & development Sympathetic Nervous System - surgery Tissue Engineering Transplants - growth & development Transplants - innervation
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