Limb Salvage Surgery in Bone Tumors: A Retrospective Study of 50 Cases in a Single Center
Modular segmental replacement system (MSRS) is one of the options for Limb conservation surgery in bone tumors. The study analyses a single center experience of use of MSRS for limb conservation in cases of primary bone tumors. Retrospective analysis was done for a series of cases of limb salvage pr...
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Veröffentlicht in: | Indian journal of surgical oncology 2013-09, Vol.4 (3), p.248-254 |
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creator | Chauhan, Ashutosh Joshi, G. R. Chopra, B. K. Ganguly, Manomoy Reddy, G. R. |
description | Modular segmental replacement system (MSRS) is one of the options for Limb conservation surgery in bone tumors. The study analyses a single center experience of use of MSRS for limb conservation in cases of primary bone tumors. Retrospective analysis was done for a series of cases of limb salvage procedures done over a five year period. All Patients with bone tumors who underwent limb salvage procedures utilising MSRS prosthesis were included in the study. The patients’ record were perused for pre operative staging; neoadjuvant therapy used, if any; surgical procedure done; follow-up for prosthesis related complications and overall survival achieved. Total of 50 cases studied,included 28 males and 22 females . Median age at diagnosis of 28 (10–73) years. Tumor localized in lower limb in 38 patients, and upper limb in 12 patients. Tumors were malignant in 28 patients (56 %) and benign in 22 (44 %). The most common diagnosis was osteosarcoma (21 patients (42 %)) . The median resection length was 15 cm (range 6–25). High grade tumors (grade 2a and 2b) was found in 27 of 29 cases(93.1 %) . 14 patients had prosthesis related complications
.
The mean follow-up was 5 years (range: 3–7). 42 patients of 50 were alive with the endoprosthesis at the last follow-up. Survival rate of prosthesis is 84 %. The modular segmental-replacement system prosthesis favoured by us in limb sparing surgery for bone tumors results in satisfactory results in terms of tumor control and limb function. |
doi_str_mv | 10.1007/s13193-013-0229-8 |
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.
The mean follow-up was 5 years (range: 3–7). 42 patients of 50 were alive with the endoprosthesis at the last follow-up. Survival rate of prosthesis is 84 %. The modular segmental-replacement system prosthesis favoured by us in limb sparing surgery for bone tumors results in satisfactory results in terms of tumor control and limb function.</description><identifier>ISSN: 0975-7651</identifier><identifier>EISSN: 0976-6952</identifier><identifier>DOI: 10.1007/s13193-013-0229-8</identifier><identifier>PMID: 24426731</identifier><language>eng</language><publisher>India: Springer India</publisher><subject>Medicine ; Medicine & Public Health ; Oncology ; Original ; Original Article ; Surgery ; Surgical Oncology</subject><ispartof>Indian journal of surgical oncology, 2013-09, Vol.4 (3), p.248-254</ispartof><rights>Indian Association of Surgical Oncology 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c442t-b1dfae9a5dd70e7eaedcd841efe8bf1cc9154f3a0213da37057a8b8aa77d7dac3</citedby><cites>FETCH-LOGICAL-c442t-b1dfae9a5dd70e7eaedcd841efe8bf1cc9154f3a0213da37057a8b8aa77d7dac3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771064/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771064/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,41488,42557,51319,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24426731$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chauhan, Ashutosh</creatorcontrib><creatorcontrib>Joshi, G. R.</creatorcontrib><creatorcontrib>Chopra, B. K.</creatorcontrib><creatorcontrib>Ganguly, Manomoy</creatorcontrib><creatorcontrib>Reddy, G. R.</creatorcontrib><title>Limb Salvage Surgery in Bone Tumors: A Retrospective Study of 50 Cases in a Single Center</title><title>Indian journal of surgical oncology</title><addtitle>Indian J Surg Oncol</addtitle><addtitle>Indian J Surg Oncol</addtitle><description>Modular segmental replacement system (MSRS) is one of the options for Limb conservation surgery in bone tumors. The study analyses a single center experience of use of MSRS for limb conservation in cases of primary bone tumors. Retrospective analysis was done for a series of cases of limb salvage procedures done over a five year period. All Patients with bone tumors who underwent limb salvage procedures utilising MSRS prosthesis were included in the study. The patients’ record were perused for pre operative staging; neoadjuvant therapy used, if any; surgical procedure done; follow-up for prosthesis related complications and overall survival achieved. Total of 50 cases studied,included 28 males and 22 females . Median age at diagnosis of 28 (10–73) years. Tumor localized in lower limb in 38 patients, and upper limb in 12 patients. Tumors were malignant in 28 patients (56 %) and benign in 22 (44 %). The most common diagnosis was osteosarcoma (21 patients (42 %)) . The median resection length was 15 cm (range 6–25). High grade tumors (grade 2a and 2b) was found in 27 of 29 cases(93.1 %) . 14 patients had prosthesis related complications
.
The mean follow-up was 5 years (range: 3–7). 42 patients of 50 were alive with the endoprosthesis at the last follow-up. Survival rate of prosthesis is 84 %. The modular segmental-replacement system prosthesis favoured by us in limb sparing surgery for bone tumors results in satisfactory results in terms of tumor control and limb function.</description><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Oncology</subject><subject>Original</subject><subject>Original Article</subject><subject>Surgery</subject><subject>Surgical Oncology</subject><issn>0975-7651</issn><issn>0976-6952</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNp9kU9LxDAQxYMorqx-AC-So5dq0rRN40HQxX-wILh68BSmzXSttM2atAv77c26uujFQEhgfu_NMI-QY87OOGPy3HPBlYgYDzeOVZTvkAOmZBZlKo13v_5pJLOUj8iR9-8sHKFEwtQ-GcVJEmdS8APyOq3bgs6gWcIc6Wxwc3QrWnf02nZIn4fWOn9Br-gT9s76BZZ9vQxcP5gVtRVNGZ2AR79WAJ3V3bxBOsGuR3dI9ipoPB59v2PycnvzPLmPpo93D5OraVSGIfqo4KYCVJAaIxlKBDSlyROOFeZFxctS8TSpBLCYCwNCslRCXuQAUhppoBRjcrnxXQxFG8ShuYNGL1zdgltpC7X-W-nqNz23Sy2k5CxLgsHpt4GzHwP6Xre1L7FpoEM7eM0TxWQWYBVQvkHLsAzvsNq24UyvU9GbVHRIRa9T0XnQnPyeb6v4ySAA8QbwodSF_et3O7gu7Owf10-qLZjg</recordid><startdate>20130901</startdate><enddate>20130901</enddate><creator>Chauhan, Ashutosh</creator><creator>Joshi, G. R.</creator><creator>Chopra, B. K.</creator><creator>Ganguly, Manomoy</creator><creator>Reddy, G. R.</creator><general>Springer India</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20130901</creationdate><title>Limb Salvage Surgery in Bone Tumors: A Retrospective Study of 50 Cases in a Single Center</title><author>Chauhan, Ashutosh ; Joshi, G. R. ; Chopra, B. K. ; Ganguly, Manomoy ; Reddy, G. R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c442t-b1dfae9a5dd70e7eaedcd841efe8bf1cc9154f3a0213da37057a8b8aa77d7dac3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Oncology</topic><topic>Original</topic><topic>Original Article</topic><topic>Surgery</topic><topic>Surgical Oncology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chauhan, Ashutosh</creatorcontrib><creatorcontrib>Joshi, G. R.</creatorcontrib><creatorcontrib>Chopra, B. K.</creatorcontrib><creatorcontrib>Ganguly, Manomoy</creatorcontrib><creatorcontrib>Reddy, G. R.</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Indian journal of surgical oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chauhan, Ashutosh</au><au>Joshi, G. R.</au><au>Chopra, B. K.</au><au>Ganguly, Manomoy</au><au>Reddy, G. R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Limb Salvage Surgery in Bone Tumors: A Retrospective Study of 50 Cases in a Single Center</atitle><jtitle>Indian journal of surgical oncology</jtitle><stitle>Indian J Surg Oncol</stitle><addtitle>Indian J Surg Oncol</addtitle><date>2013-09-01</date><risdate>2013</risdate><volume>4</volume><issue>3</issue><spage>248</spage><epage>254</epage><pages>248-254</pages><issn>0975-7651</issn><eissn>0976-6952</eissn><abstract>Modular segmental replacement system (MSRS) is one of the options for Limb conservation surgery in bone tumors. The study analyses a single center experience of use of MSRS for limb conservation in cases of primary bone tumors. Retrospective analysis was done for a series of cases of limb salvage procedures done over a five year period. All Patients with bone tumors who underwent limb salvage procedures utilising MSRS prosthesis were included in the study. The patients’ record were perused for pre operative staging; neoadjuvant therapy used, if any; surgical procedure done; follow-up for prosthesis related complications and overall survival achieved. Total of 50 cases studied,included 28 males and 22 females . Median age at diagnosis of 28 (10–73) years. Tumor localized in lower limb in 38 patients, and upper limb in 12 patients. Tumors were malignant in 28 patients (56 %) and benign in 22 (44 %). The most common diagnosis was osteosarcoma (21 patients (42 %)) . The median resection length was 15 cm (range 6–25). High grade tumors (grade 2a and 2b) was found in 27 of 29 cases(93.1 %) . 14 patients had prosthesis related complications
.
The mean follow-up was 5 years (range: 3–7). 42 patients of 50 were alive with the endoprosthesis at the last follow-up. Survival rate of prosthesis is 84 %. The modular segmental-replacement system prosthesis favoured by us in limb sparing surgery for bone tumors results in satisfactory results in terms of tumor control and limb function.</abstract><cop>India</cop><pub>Springer India</pub><pmid>24426731</pmid><doi>10.1007/s13193-013-0229-8</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Medicine Medicine & Public Health Oncology Original Original Article Surgery Surgical Oncology |
title | Limb Salvage Surgery in Bone Tumors: A Retrospective Study of 50 Cases in a Single Center |
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