Germline Missense Variants in the BTNL2 Gene Are Associated with Prostate Cancer Susceptibility

Rare, inherited mutations account for 5% to 10% of all prostate cancer cases. However, to date, few causative mutations have been identified. To identify rare mutations for prostate cancer, we conducted whole-exome sequencing (WES) in multiple kindreds (n = 91) from 19 hereditary prostate cancer (HP...

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Veröffentlicht in:Cancer epidemiology, biomarkers & prevention biomarkers & prevention, 2013-09, Vol.22 (9), p.1520-1528
Hauptverfasser: FITZGERALD, Liesel M, KUMAR, Akash, LI HSU, SHENDURE, Jay, STANFORD, Janet L, BOYLE, Evan A, YUZHENG ZHANG, MCINTOSH, Laura M, KOLB, Suzanne, STOTT-MILLER, Marni, SMITH, Tiffany, KARYADI, Danielle M, OSTRANDER, Elaine A
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Sprache:eng
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