Cartilage to bone transitions in health and disease

Aberrant redeployment of the ‘transient’ events responsible for bone development and postnatal longitudinal growth has been reported in some diseases in what is otherwise inherently ‘stable’ cartilage. Lessons may be learnt from the molecular mechanisms underpinning transient chondrocyte differentia...

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Veröffentlicht in:	Journal of endocrinology 2013-10, Vol.219 (1), p.R1-R12
Hauptverfasser:	Staines, K A, Pollard, A S, McGonnell, I M, Farquharson, C, Pitsillides, A A
Format:	Artikel
Sprache:	eng
Schlagworte:	Bone Development - physiology Bone Diseases - physiopathology Cartilage - growth & development Cartilage - physiology Cartilage, Articular - cytology Cartilage, Articular - pathology Cell Differentiation Chondrocytes - cytology Chondrocytes - physiology Epiphyses Growth Plate - cytology Humans Intervertebral Disc Degeneration - physiopathology Ossification, Heterotopic - physiopathology Osteoarthritis - pathology Osteogenesis - physiology Phenotype Review
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