Improved HPLC Method Using 2,3-naphthalenedicarboxaldehyde as Fluorescent Labeling Agent for Quantification of Histamine in Human Immunoglobulin Preparations

To develop and optimize quantitative HPLC method using 2,3-naphthalenedicarboxaldehyde (NDA) after simple and efficient solid phase extraction to determine the histamine in a biopharmaceutical (Histobulin™). The HPLC method was established using NDA-induced Histobulin and compared with the recently...

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Veröffentlicht in:	Osong public health and research perspectives 2011-09, Vol.2 (2), p.127-134
Hauptverfasser:	Kim, Jung-Hwan, Shin, In Soo, Lee, Yoo Kyoung, Oh, Ho Jung, Ban, Sang Ja
Format:	Artikel
Sprache:	eng
Schlagworte:	2,3-naphthalenedi-carboxaldehye (NDA) high-performance liquid chromatography (HPLC) histamine immunoglobulin (Ig) preparation lot-release test Original
Online-Zugang:	Volltext
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