Healthy ageing and depletion of intracellular glutathione influences T cell membrane thioredoxin-1 levels and cytokine secretion

Background During ageing an altered redox balance has been observed in both intracellular and extracellular compartments, primarily due to glutathione depletion and metabolic stress. Maintaining redox homeostasis is important for controlling proliferation and apoptosis in response to specific stimul...

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Veröffentlicht in:	BMC chemistry 2013-09, Vol.7 (1), p.150-150, Article 150
Hauptverfasser:	Carilho Torrao, Rita Barreto Duarte, Dias, Irundika HK, Bennett, Stuart J, Dunston, Christopher R, Griffiths, Helen R
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Apoptosis Biological Chemistry Cell culture Cell growth Chemistry Chemistry and Materials Science Chemistry/Food Science Compartments Cytomegalovirus Depletion Enzymes Flow cytometry Glutathione Immune system Kinases Lymphocytes Nitrogen Proteins Research Article Secretions
Online-Zugang:	Volltext
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