Retinal Endothelial Cell Apoptosis Stimulates Recruitment of Endothelial Progenitor Cells

Bone marrow-derived endothelial progenitor cells (EPCs) contribute to vascular repair although it is uncertain how local endothelial cell apoptosis influences their reparative function. This study was conducted to determine how the presence of apoptotic bodies at sites of endothelial damage may infl...

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Veröffentlicht in:	Investigative ophthalmology & visual science 2009-10, Vol.50 (10), p.4967-4973
Hauptverfasser:	Bhatwadekar, Ashay D, Glenn, Josephine V, Curtis, Tim M, Grant, Maria B, Stitt, Alan W, Gardiner, Tom A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Biological and medical sciences Capillaries - cytology Cattle Cell Adhesion - physiology Cell Movement - physiology Cells, Cultured Chemotaxis - physiology Cytokines - metabolism E-Selectin - genetics E-Selectin - metabolism Endothelium, Vascular - drug effects Endothelium, Vascular - physiology Enzyme-Linked Immunosorbent Assay Eye and associated structures. Visual pathways and centers. Vision Flow Cytometry Fluorescent Antibody Technique, Indirect Fundamental and applied biological sciences. Psychology Intercellular Adhesion Molecule-1 - genetics Intercellular Adhesion Molecule-1 - metabolism Medical sciences Ophthalmology Photosensitizing Agents - toxicity Porphyrins - toxicity Retinal Vessels - cytology Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism Stem Cells - physiology Up-Regulation Vascular Cell Adhesion Molecule-1 - genetics Vascular Cell Adhesion Molecule-1 - metabolism Vascular Endothelial Growth Factor A - metabolism Vertebrates: nervous system and sense organs Wound Healing - physiology
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