NPEBseq: nonparametric empirical bayesian-based procedure for differential expression analysis of RNA-seq data

RNA-seq, a massive parallel-sequencing-based transcriptome profiling method, provides digital data in the form of aligned sequence read counts. The comparative analyses of the data require appropriate statistical methods to estimate the differential expression of transcript variants across different...

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Veröffentlicht in:	BMC bioinformatics 2013-08, Vol.14 (1), p.262-262, Article 262
Hauptverfasser:	Bi, Yingtao, Davuluri, Ramana V
Format:	Artikel
Sprache:	eng
Schlagworte:	Bayes Theorem Bayesian analysis Bayesian statistical decision theory Binomial distribution Bioinformatics Comparative analysis Computational Biology - methods Counting Digital data DNA binding proteins Empirical analysis Gene expression Gene Expression Profiling - methods Generalized linear models Genes Genomics High-Throughput Nucleotide Sequencing Packages RNA - analysis RNA - genetics RNA sequencing Sequence Alignment Sequence Analysis, RNA - methods Software Statistical methods Statistics, Nonparametric Studies
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