Mesenchymal Stem/Progenitors and Other Endometrial Cell Types From Women With Polycystic Ovary Syndrome (PCOS) Display Inflammatory and Oncogenic Potential

Context: Endometrium in polycystic ovary syndrome (PCOS) presents altered gene expression indicating progesterone resistance and predisposing to reduced endometrial receptivity and endometrial cancer. Objective: We hypothesized that an altered endocrine/metabolic environment in PCOS may result in an...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2013-09, Vol.98 (9), p.3765-3775
Hauptverfasser:	Piltonen, T. T, Chen, J, Erikson, D. W, Spitzer, T. L. B, Barragan, F, Rabban, J. T, Huddleston, H, Irwin, J. C, Giudice, L. C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Body Mass Index Cell Proliferation Endocrine Research Endocrinopathies Endometrium - metabolism Endometrium - pathology Feeding. Feeding behavior Female Fundamental and applied biological sciences. Psychology Gene Expression Humans Inflammation - genetics Inflammation - metabolism Inflammation - pathology Interleukin-6 - genetics Interleukin-6 - metabolism Interleukin-8 - genetics Interleukin-8 - metabolism Medical sciences Mesenchymal Stromal Cells - metabolism Mesenchymal Stromal Cells - pathology Obesity - genetics Obesity - metabolism Obesity - pathology Overweight - genetics Overweight - metabolism Overweight - pathology Polycystic Ovary Syndrome - genetics Polycystic Ovary Syndrome - metabolism Polycystic Ovary Syndrome - pathology Up-Regulation Vertebrates: anatomy and physiology, studies on body, several organs or systems Vertebrates: endocrinology
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