The Structure of the Mercury Transporter MerF in Phospholipid Bilayers: A Large Conformational Rearrangement Results from N‑Terminal Truncation

The three-dimensional structure of the 81-residue mercury transporter MerF determined in liquid crystalline phospholipid bilayers under physiological conditions by Rotationally Aligned (RA) solid-state NMR has two long helices, which extend well beyond the bilayer, with a well-defined interhelical l...

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Veröffentlicht in:	Journal of the American Chemical Society 2013-06, Vol.135 (25), p.9299-9302
Hauptverfasser:	Lu, George J, Tian, Ye, Vora, Nemil, Marassi, Francesca M, Opella, Stanley J
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Bacterial Proteins - chemistry Cation Transport Proteins - chemistry Lipid Bilayers - chemistry Models, Molecular Molecular Sequence Data Nuclear Magnetic Resonance, Biomolecular Phospholipids - chemistry Protein Conformation
Online-Zugang:	Volltext
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