DNA double-strand-break complexity levels and their possible contributions to the probability for error-prone processing and repair pathway choice

Although the DNA double-strand break (DSB) is defined as a rupture in the double-stranded DNA molecule that can occur without chemical modification in any of the constituent building blocks, it is recognized that this form is restricted to enzyme-induced DSBs. DSBs generated by physical or chemical...

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Veröffentlicht in:	Nucleic acids research 2013-09, Vol.41 (16), p.7589-7605
Hauptverfasser:	Schipler, Agnes, Iliakis, George
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA Breaks, Double-Stranded DNA Repair Models, Molecular Survey and Summary
Online-Zugang:	Volltext
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