The potential economic value of a cutaneous leishmaniasis vaccine in seven endemic countries in the Americas
Highlights ► We constructed and utilized a computer simulation model to evaluate the economic value of a CL vaccine. ► Modest protection duration and efficacy are required for CL vaccination to cost less than treatment. ► A preventative CL vaccine could save costs at moderate levels of infection ris...
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| Veröffentlicht in: | Vaccine 2013-01, Vol.31 (3), p.480-486 |
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| container_end_page | 486 |
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| container_issue | 3 |
| container_start_page | 480 |
| container_title | Vaccine |
| container_volume | 31 |
| creator | Bacon, Kristina M Hotez, Peter J Kruchten, Stephanie D Kamhawi, Shaden Bottazzi, Maria Elena Valenzuela, Jesus G Lee, Bruce Y |
| description | Highlights ► We constructed and utilized a computer simulation model to evaluate the economic value of a CL vaccine. ► Modest protection duration and efficacy are required for CL vaccination to cost less than treatment. ► A preventative CL vaccine could save costs at moderate levels of infection risk. |
| doi_str_mv | 10.1016/j.vaccine.2012.11.032 |
| format | Article |
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Psychology ; Health risks ; Humans ; Infections ; Latin America ; Leishmaniasis Vaccines - administration & dosage ; Leishmaniasis Vaccines - economics ; Leishmaniasis Vaccines - immunology ; Leishmaniasis, Cutaneous - economics ; Leishmaniasis, Cutaneous - epidemiology ; Leishmaniasis, Cutaneous - prevention & control ; Mexico ; Microbiology ; Parasites ; Parasitic diseases ; Peru ; Sand & gravel ; Skin ; Vaccine ; Vaccines ; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) ; Vector-borne diseases ; Venezuela</subject><ispartof>Vaccine, 2013-01, Vol.31 (3), p.480-486</ispartof><rights>Elsevier Ltd</rights><rights>2012 Elsevier Ltd</rights><rights>2014 INIST-CNRS</rights><rights>Copyright © 2012 Elsevier Ltd. All rights reserved.</rights><rights>Copyright Elsevier Limited Jan 7, 2013</rights><rights>2012 Elsevier Ltd. 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| fulltext | fulltext |
| identifier | ISSN: 0264-410X |
| ispartof | Vaccine, 2013-01, Vol.31 (3), p.480-486 |
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| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3763201 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Allergy and Immunology Americas - epidemiology Antigens Applied microbiology Biological and medical sciences Bolivia Brazil chaparral Chemotherapy Colombia Computer Simulation cost effectiveness Costs and Cost Analysis Cutaneous leishmaniasis deforestation Drug dosages drug therapy economic valuation Economics Ecuador Endemic Diseases - economics Endemic Diseases - prevention & control Fundamental and applied biological sciences. Psychology Health risks Humans Infections Latin America Leishmaniasis Vaccines - administration & dosage Leishmaniasis Vaccines - economics Leishmaniasis Vaccines - immunology Leishmaniasis, Cutaneous - economics Leishmaniasis, Cutaneous - epidemiology Leishmaniasis, Cutaneous - prevention & control Mexico Microbiology Parasites Parasitic diseases Peru Sand & gravel Skin Vaccine Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Vector-borne diseases Venezuela |
| title | The potential economic value of a cutaneous leishmaniasis vaccine in seven endemic countries in the Americas |
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