Nanoliposomal minocycline for ocular drug delivery

Abstract Nanoliposomal technology is a promising drug delivery system that could be employed to improve the pharmacokinetic properties of clearance and distribution in ocular drug delivery to the retina. We developed a nanoscale version of an anionic, cholesterol-fusing liposome that can encapsulate...

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Veröffentlicht in:	Nanomedicine 2013-01, Vol.9 (1), p.130-140
Hauptverfasser:	Kaiser, James M., MS, Imai, Hisanori, MD, Haakenson, Jeremy K., BS, Brucklacher, Robert M., MS, Fox, Todd E., PhD, Shanmugavelandy, Sriram S., MS, Unrath, Kellee A., BS, Pedersen, Michelle M., BS, Dai, Pingqi, MS, Freeman, Willard M., PhD, Bronson, Sarah K., PhD, Gardner, Thomas W., MD, Kester, Mark, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Ophthalmic Animals Anti-Bacterial Agents - administration & dosage biomarkers Blotting, Western Chromatography Diabetes mellitus Diabetic retinopathy Drug delivery Enzyme-Linked Immunosorbent Assay Inflammation Internal Medicine Liposomes Minocycline Minocycline - administration & dosage mRNA Nanotechnology Pharmacokinetics Polymerase Chain Reaction proteomics Rats Retina Transcriptomics
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