Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods

Recent advancements in sequencing-based DNA methylation profiling methods provide an unprecedented opportunity to map complete DNA methylomes. These include whole-genome bisulfite sequencing (WGBS, MethylC-seq, or BS-seq), reduced-representation bisulfite sequencing (RRBS), and enrichment-based meth...

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Veröffentlicht in:	Genome research 2013-09, Vol.23 (9), p.1541-1553
Hauptverfasser:	Stevens, Michael, Cheng, Jeffrey B, Li, Daofeng, Xie, Mingchao, Hong, Chibo, Maire, Cécile L, Ligon, Keith L, Hirst, Martin, Marra, Marco A, Costello, Joseph F, Wang, Ting
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms CpG Islands DNA Methylation DNA Restriction Enzymes - chemistry Genome, Human Humans Method Sequence Analysis, DNA - methods Software
Online-Zugang:	Volltext
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