SOX2 promotes dedifferentiation and imparts stem cell-like features to pancreatic cancer cells

SOX2 (Sex-determining region Y (SRY)-Box2) has important functions during embryonic development and is involved in cancer stem cell (CSC) maintenance, in which it impairs cell growth and tumorigenicity. However, the function of SOX2 in pancreatic cancer cells is unclear. The objective of this study...

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Veröffentlicht in:	Oncogenesis (New York, NY) NY), 2013-08, Vol.2 (8), p.e61-e61
Hauptverfasser:	Herreros-Villanueva, M, Zhang, J-S, Koenig, A, Abel, E V, Smyrk, T C, Bamlet, W R, de Narvajas, A A-M, Gomez, T S, Simeone, D M, Bujanda, L, Billadeau, D D
Format:	Artikel
Sprache:	eng
Schlagworte:	631/337 631/67/1504/1713 631/67/71 Apoptosis Cell Biology Human Genetics Internal Medicine Medicine Medicine & Public Health Oncology Original original-article
Online-Zugang:	Volltext
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