Anxiety and fear in a cross of C57BL/6J and DBA/2J mice: mapping overlapping and independent QTL for related traits

Anxiety, like other psychiatric disorders, is a complex neurobehavioral trait, making identification of causal genes difficult. In this study, we examined anxiety‐like behavior and fear conditioning (FC) in an F2 intercross of C57BL/6J and DBA/2J mice. We identified numerous quantitative trait loci...

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Veröffentlicht in:	Genes, brain and behavior brain and behavior, 2011-07, Vol.10 (5), p.604-614
Hauptverfasser:	Sokoloff, G., Parker, C. C., Lim, J. E., Palmer, A. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anxiety Anxiety - genetics Behavior Behavior, Animal - physiology Conditioning (Psychology) - physiology Crosses, Genetic fear Fear - physiology fear conditioning Female Gene loci Genomics Genotype Male Mice Mice, Inbred C57BL Mice, Inbred DBA Motor Activity - genetics open field Phenotype QTL QTL modeling Quantitative Trait Loci
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