Deciphering the proteome of the in vivo diagnostic reagent "purified protein derivative" from Mycobacterium tuberculosis

Purified protein derivative (PPD) has served as a safe and effective diagnostic reagent for 60 years and is the only broadly available material to diagnose latent tuberculosis infections. This reagent is also used as a standard control for a number of in vitro immunological assays. Nevertheless, the...

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Veröffentlicht in:	Proteomics (Weinheim) 2012-04, Vol.12 (7), p.979-991
Hauptverfasser:	Cho, Yun Sang, Dobos, Karen M., Prenni, Jessica, Yang, Hongliang, Hess, Ann, Rosenkrands, Ida, Andersen, Peter, Ryoo, Sung Weon, Bai, Gill-Han, Brennan, Michael J., Izzo, Angelo, Bielefeldt-Ohmann, Helle, Belisle, John T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Animals Antigens, Bacterial - analysis Antigens, Bacterial - chemistry Antigens, Bacterial - classification Antigens, Bacterial - immunology Bacterial Proteins - analysis Bacterial Proteins - chemistry Bacterial Proteins - classification Bacterial Proteins - immunology Biological and medical sciences DTH/Microbiology Fundamental and applied biological sciences. Psychology Guinea Pigs Miscellaneous Mycobacterium tuberculosis Mycobacterium tuberculosis - chemistry Mycobacterium tuberculosis - immunology PPD Proteins Proteome - analysis Proteome - chemistry Tuberculin - analysis Tuberculin - chemistry Tuberculin - immunology Tuberculosis Tuberculosis - immunology Tuberculosis - microbiology
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