Genome-Wide Association Study of Intracranial Aneurysms Confirms Role of Anril and SOX17 in Disease Risk

Genomewide association studies have identified novel genetic factors that contribute to intracranial aneurysm (IA) susceptibility. We sought to confirm previously reported loci, to identify novel risk factors, and to evaluate the contribution of these factors to familial and sporadic IA. We utilized...

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Veröffentlicht in:	Stroke (1970) 2012-11, Vol.43 (11), p.2846-2852
Hauptverfasser:	FOROUD, Tatiana, KOLLER, Daniel L, MOOMAW, Charles J, HORNUNG, Richard, HUSTON, John, MEISSNER, Irene, BAILEY-WILSON, Joan E, LANGEFELD, Carl, ROULEAU, Guy, CONNOLLY, E. Sander, WORRALL, Bradford B, KLEINDORFER, Dawn, DONGBING LAI, FLAHERTY, Matthew L, MARTINI, Sharyl, MACKEY, Jason, DE LOS RIOS LA ROSA, Felipe, BROWN, Robert D, BRODERICK, Joseph P, SAUERBECK, Laura, ANDERSON, Craig, KO, Nerissa, DEKA, Ranjan, MOSLEY, Thomas H, FORNAGE, Myriam, WOO, Daniel
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Diseases of the nervous system Genetic Predisposition to Disease - genetics Genome-Wide Association Study Genotype Humans Intracranial Aneurysm - genetics Medical sciences Neurology Polymorphism, Single Nucleotide Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Risk Factors RNA, Long Noncoding - genetics Smoking - adverse effects SOXF Transcription Factors - genetics Vascular diseases and vascular malformations of the nervous system
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