Aspirin: a review of its neurobiological properties and therapeutic potential for mental illness

There is compelling evidence to support an aetiological role for inflammation, oxidative and nitrosative stress (O&NS), and mitochondrial dysfunction in the pathophysiology of major neuropsychiatric disorders, including depression, schizophrenia, bipolar disorder, and Alzheimer's disease (A...

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Veröffentlicht in:	BMC medicine 2013-03, Vol.11 (1), p.74-74, Article 74
Hauptverfasser:	Berk, Michael, Dean, Olivia, Drexhage, Hemmo, McNeil, John J, Moylan, Steven, O'Neil, Adrienne, Davey, Christopher G, Sanna, Livia, Maes, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Animals Anti-Inflammatory Agents, Non-Steroidal - pharmacology Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Aspirin Aspirin - pharmacology Aspirin - therapeutic use Bipolar disorder C-reactive protein Complications and side effects Cytokines Depression, Mental Dosage and administration Drug therapy Encephalitis - drug therapy Encephalitis - metabolism Encephalitis - psychology Epidemiology Humans Immune system Inflammation Interleukins Medical research Medicine, Experimental Mental Disorders - drug therapy Mental Disorders - metabolism Mental Disorders - psychology Opinion Oxidative Stress - drug effects Oxidative Stress - physiology Reactive Oxygen Species - antagonists & inhibitors Reactive Oxygen Species - metabolism Schizophrenia
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