The human microbiota: a new direction in the investigation of thoracic diseases

Advancements in next generation sequencing technology have provided means for the comprehensive profiling of the microbial community in the respiratory tract in both physiological and pathological conditions. Recent studies have analyzed the bacterial composition in the respiratory tract of chronic...

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Veröffentlicht in:Journal of thoracic disease 2013-08, Vol.5 Suppl 2 (Suppl 2), p.S127-S131
Hauptverfasser: Hui, Anselm Wang-Hei, Lau, Hon-Wai, Chan, Tiffany Hoi-Tung, Tsui, Stephen Kwok-Wing
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container_end_page S131
container_issue Suppl 2
container_start_page S127
container_title Journal of thoracic disease
container_volume 5 Suppl 2
creator Hui, Anselm Wang-Hei
Lau, Hon-Wai
Chan, Tiffany Hoi-Tung
Tsui, Stephen Kwok-Wing
description Advancements in next generation sequencing technology have provided means for the comprehensive profiling of the microbial community in the respiratory tract in both physiological and pathological conditions. Recent studies have analyzed the bacterial composition in the respiratory tract of chronic obstructive pulmonary disease (COPD), influenza and tuberculosis patients, and have identified novel targets that may potentially lead to secondary infections. Certain bacteria have also been found to regulate the lung immune system and have unexpected connections with respiratory diseases. Further studies in these areas are necessary to dissect the exact relationship between the dynamics of the microbiota and the health of the respiratory system.
doi_str_mv 10.3978/j.issn.2072-1439.2013.07.41
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title The human microbiota: a new direction in the investigation of thoracic diseases
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