TRIM Proteins in Therapeutic Membrane Repair of Muscular Dystrophy

Muscular dystrophy represents a major unmet medical need; only palliative treatments exist for this group of debilitating diseases. Because multiple forms of muscular dystrophy arise from compromised sarcolemmal membrane integrity, a therapeutic approach that can target this loss of membrane functio...

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Veröffentlicht in:	JAMA neurology 2013-07, Vol.70 (7), p.1-5
Hauptverfasser:	Alloush, Jenna, Weisleder, Noah
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - genetics Adaptor Proteins, Signal Transducing - therapeutic use Amino Acid Motifs - genetics Carrier Proteins - genetics Carrier Proteins - metabolism Carrier Proteins - therapeutic use Cell Membrane - drug effects Cell Membrane - genetics Cell Membrane - metabolism Humans Membrane Proteins - genetics Membrane Proteins - therapeutic use Muscle Weakness - genetics Muscular Dystrophies - drug therapy Muscular Dystrophies - metabolism Tripartite Motif Proteins
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