Management of Hyperglycemia During Enteral and Parenteral Nutrition Therapy
Hyperglycemia is a frequent complication of enteral and parenteral nutrition in hospitalized patients. Extensive evidence from observational studies indicates that the development of hyperglycemia during parenteral and enteral nutrition is associated with an increased risk of death and infectious co...
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| Veröffentlicht in: | Current diabetes reports 2013-02, Vol.13 (1), p.155-162 |
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| creator | Gosmanov, Aidar R. Umpierrez, Guillermo E. |
| description | Hyperglycemia is a frequent complication of enteral and parenteral nutrition in hospitalized patients. Extensive evidence from observational studies indicates that the development of hyperglycemia during parenteral and enteral nutrition is associated with an increased risk of death and infectious complications. There are no specific guidelines recommending glycemic targets and effective strategies for the management of hyperglycemia during specialized nutritional support. Managing hyperglycemia in these patients should include optimization of carbohydrate content and administration of intravenous or subcutaneous insulin therapy. The administration of continuous insulin infusion and insulin addition to nutrition bag are efficient approaches to control hyperglycemia during parenteral nutrition. Subcutaneous administration of long-acting insulin with scheduled or corrective doses of short-acting insulin is superior to the sliding scale insulin strategy in patients receiving enteral feedings. Randomized controlled studies are needed to evaluate safe and effective therapeutic strategies for the management of hyperglycemia in patients receiving nutritional support. |
| doi_str_mv | 10.1007/s11892-012-0335-y |
| format | Article |
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Extensive evidence from observational studies indicates that the development of hyperglycemia during parenteral and enteral nutrition is associated with an increased risk of death and infectious complications. There are no specific guidelines recommending glycemic targets and effective strategies for the management of hyperglycemia during specialized nutritional support. Managing hyperglycemia in these patients should include optimization of carbohydrate content and administration of intravenous or subcutaneous insulin therapy. The administration of continuous insulin infusion and insulin addition to nutrition bag are efficient approaches to control hyperglycemia during parenteral nutrition. Subcutaneous administration of long-acting insulin with scheduled or corrective doses of short-acting insulin is superior to the sliding scale insulin strategy in patients receiving enteral feedings. Randomized controlled studies are needed to evaluate safe and effective therapeutic strategies for the management of hyperglycemia in patients receiving nutritional support.</description><identifier>ISSN: 1534-4827</identifier><identifier>EISSN: 1539-0829</identifier><identifier>DOI: 10.1007/s11892-012-0335-y</identifier><identifier>PMID: 23065369</identifier><language>eng</language><publisher>New York: Current Science Inc</publisher><subject>Diabetes ; Diet ; Enteral Nutrition - adverse effects ; Hospital Management of Diabetes (G Umpierrez ; Humans ; Hyperglycemia - diet therapy ; Hyperglycemia - drug therapy ; Hyperglycemia - etiology ; Insulin - therapeutic use ; Medicine ; Medicine & Public Health ; Parenteral Nutrition - adverse effects ; Section Editor</subject><ispartof>Current diabetes reports, 2013-02, Vol.13 (1), p.155-162</ispartof><rights>Springer Science+Business Media New York 2012</rights><rights>Springer Science+Business Media New York 2013</rights><rights>Springer Science+Business Media New York 2012 2012</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-p337t-e0df5969e52e90c2dad4a4d761df919612ddf245d6f4a58259a4eb659664cd2c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11892-012-0335-y$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11892-012-0335-y$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>230,314,776,780,881,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23065369$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gosmanov, Aidar R.</creatorcontrib><creatorcontrib>Umpierrez, Guillermo E.</creatorcontrib><title>Management of Hyperglycemia During Enteral and Parenteral Nutrition Therapy</title><title>Current diabetes reports</title><addtitle>Curr Diab Rep</addtitle><addtitle>Curr Diab Rep</addtitle><description>Hyperglycemia is a frequent complication of enteral and parenteral nutrition in hospitalized patients. Extensive evidence from observational studies indicates that the development of hyperglycemia during parenteral and enteral nutrition is associated with an increased risk of death and infectious complications. There are no specific guidelines recommending glycemic targets and effective strategies for the management of hyperglycemia during specialized nutritional support. Managing hyperglycemia in these patients should include optimization of carbohydrate content and administration of intravenous or subcutaneous insulin therapy. The administration of continuous insulin infusion and insulin addition to nutrition bag are efficient approaches to control hyperglycemia during parenteral nutrition. Subcutaneous administration of long-acting insulin with scheduled or corrective doses of short-acting insulin is superior to the sliding scale insulin strategy in patients receiving enteral feedings. Randomized controlled studies are needed to evaluate safe and effective therapeutic strategies for the management of hyperglycemia in patients receiving nutritional support.</description><subject>Diabetes</subject><subject>Diet</subject><subject>Enteral Nutrition - adverse effects</subject><subject>Hospital Management of Diabetes (G Umpierrez</subject><subject>Humans</subject><subject>Hyperglycemia - diet therapy</subject><subject>Hyperglycemia - drug therapy</subject><subject>Hyperglycemia - etiology</subject><subject>Insulin - therapeutic use</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Parenteral Nutrition - adverse effects</subject><subject>Section Editor</subject><issn>1534-4827</issn><issn>1539-0829</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNpdkclOwzAURS0EomX4ADYoEhs2Ac-JN0ioFIoow6KsLTd20lSJE5wEKX-PQwsqLCxP511fvwvAGYJXCMLoukEoFjiEyA9CWNjvgTFiRIQwxmL_e01DGuNoBI6aZg0h9lXsEIwwgZwRLsbg6VlZlZnS2Dao0mDW18ZlRZ-YMlfBXedymwVT2xqnikBZHbwpZ7bbl651eZtXNlis_EHdn4CDVBWNOd3Ox-D9frqYzML568Pj5HYe1oREbWigTpngwjBsBEywVpoqqiOOdCqQ4AhrnWLKNE-pYjFmQlGz5L6E00TjhByDm41u3S1LoxNvyPuRtctL5XpZqVz-vbH5SmbVpyQR5VQgL3C5FXDVR2eaVpZ5k5iiUNZUXSMRjggVw4MevfiHrqvOWf89iThjBLJIQE-d7zr6tfLTZw_gDdDUQ0uN25GBcghTbsKUPkw5hCl78gU6TJDJ</recordid><startdate>20130201</startdate><enddate>20130201</enddate><creator>Gosmanov, Aidar R.</creator><creator>Umpierrez, Guillermo E.</creator><general>Current Science Inc</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20130201</creationdate><title>Management of Hyperglycemia During Enteral and Parenteral Nutrition Therapy</title><author>Gosmanov, Aidar R. ; 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Extensive evidence from observational studies indicates that the development of hyperglycemia during parenteral and enteral nutrition is associated with an increased risk of death and infectious complications. There are no specific guidelines recommending glycemic targets and effective strategies for the management of hyperglycemia during specialized nutritional support. Managing hyperglycemia in these patients should include optimization of carbohydrate content and administration of intravenous or subcutaneous insulin therapy. The administration of continuous insulin infusion and insulin addition to nutrition bag are efficient approaches to control hyperglycemia during parenteral nutrition. Subcutaneous administration of long-acting insulin with scheduled or corrective doses of short-acting insulin is superior to the sliding scale insulin strategy in patients receiving enteral feedings. Randomized controlled studies are needed to evaluate safe and effective therapeutic strategies for the management of hyperglycemia in patients receiving nutritional support.</abstract><cop>New York</cop><pub>Current Science Inc</pub><pmid>23065369</pmid><doi>10.1007/s11892-012-0335-y</doi><tpages>8</tpages></addata></record> |
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| ispartof | Current diabetes reports, 2013-02, Vol.13 (1), p.155-162 |
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| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Diabetes Diet Enteral Nutrition - adverse effects Hospital Management of Diabetes (G Umpierrez Humans Hyperglycemia - diet therapy Hyperglycemia - drug therapy Hyperglycemia - etiology Insulin - therapeutic use Medicine Medicine & Public Health Parenteral Nutrition - adverse effects Section Editor |
| title | Management of Hyperglycemia During Enteral and Parenteral Nutrition Therapy |
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