CMV reactivation after allogeneic HCT and relapse risk: evidence for early protection in acute myeloid leukemia

The association between cytomegalovirus (CMV) reactivation and relapse was evaluated in a large cohort of patients with acute myeloid leukemia (AML) (n = 761), acute lymphoblastic leukemia (ALL) (n = 322), chronic myeloid leukemia (CML) (n = 646), lymphoma (n = 254), and myelodysplastic syndrome (MD...

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Veröffentlicht in:	Blood 2013-08, Vol.122 (7), p.1316-1324
Hauptverfasser:	Green, Margaret L., Leisenring, Wendy M., Xie, Hu, Walter, Roland B., Mielcarek, Marco, Sandmaier, Brenda M., Riddell, Stanley R., Boeckh, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Child Child, Preschool Cytomegalovirus - physiology Cytomegalovirus Infections - etiology Cytomegalovirus Infections - mortality Cytomegalovirus Infections - prevention & control Female Follow-Up Studies Graft vs Host Disease - etiology Graft vs Host Disease - mortality Graft vs Host Disease - prevention & control Hematopoietic Stem Cell Transplantation - adverse effects Humans Infant Infant, Newborn Leukemia, Myelogenous, Chronic, BCR-ABL Positive - complications Leukemia, Myelogenous, Chronic, BCR-ABL Positive - prevention & control Leukemia, Myelogenous, Chronic, BCR-ABL Positive - virology Leukemia, Myeloid, Acute - complications Leukemia, Myeloid, Acute - prevention & control Leukemia, Myeloid, Acute - virology Lymphoma - complications Lymphoma - prevention & control Lymphoma - virology Male Myelodysplastic Syndromes - complications Myelodysplastic Syndromes - prevention & control Myelodysplastic Syndromes - virology Neoplasm Recurrence, Local - mortality Neoplasm Recurrence, Local - prevention & control Neoplasm Recurrence, Local - virology Phosphoproteins - blood Phosphoproteins - immunology Precursor Cell Lymphoblastic Leukemia-Lymphoma - complications Precursor Cell Lymphoblastic Leukemia-Lymphoma - prevention & control Precursor Cell Lymphoblastic Leukemia-Lymphoma - virology Prognosis Retrospective Studies Risk Factors Survival Rate Transplantation Transplantation Conditioning Transplantation, Homologous Viral Matrix Proteins - blood Viral Matrix Proteins - immunology Virus Activation Young Adult
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