Tango7 directs cellular remodeling by the Drosophila apoptosome

It is now well appreciated that the apoptosome, which governs caspase-dependent cell death, also drives nonapoptotic caspase activation to remodel cells. However, the determinants that specify whether the apoptosome acts to kill or remodel have yet to be identified. Here we report that Tango7 collab...

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Veröffentlicht in:	Genes & development 2013-08, Vol.27 (15), p.1650-1655
Hauptverfasser:	D'Brot, Alejandro, Chen, Po, Vaishnav, Mahesh, Yuan, Shujun, Akey, Christopher W, Abrams, John M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosomes - metabolism Aryl Hydrocarbon Receptor Nuclear Translocator - genetics Aryl Hydrocarbon Receptor Nuclear Translocator - metabolism Caspases - metabolism Drosophila Drosophila melanogaster - cytology Drosophila melanogaster - enzymology Drosophila Proteins - genetics Drosophila Proteins - metabolism Fertility - genetics Genetic Variation Male Mutation Research Communication Spermatogenesis - genetics Spermatozoa - enzymology Spermatozoa - metabolism
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