Recent trends in microdialysis sampling integrated with conventional and microanalytical systems for monitoring biological events: A review
Microdialysis (MD) is a sampling technique that can be employed to monitor biological events both in vivo and in vitro. When it is coupled to an analytical system, microdialysis can provide near real-time information on the time-dependent concentration changes of analytes in the extracellular space...
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| Veröffentlicht in: | Analytica chimica acta 2009-09, Vol.651 (1), p.1-14 |
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| creator | Nandi, Pradyot Lunte, Susan M. |
| description | Microdialysis (MD) is a sampling technique that can be employed to monitor biological events both
in vivo and
in vitro. When it is coupled to an analytical system, microdialysis can provide near real-time information on the time-dependent concentration changes of analytes in the extracellular space or other aqueous environments. Online systems for the analysis of microdialysis samples enable fast, selective and sensitive analysis while preserving the temporal information. Analytical methods employed for online analysis include liquid chromatography (LC), capillary (CE) and microchip electrophoresis and flow-through biosensor devices. This review article provides an overview of microdialysis sampling and online analysis systems with emphasis on
in vivo analysis. Factors that affect the frequency of analysis and, hence, the temporal resolution of these systems are also discussed. |
| doi_str_mv | 10.1016/j.aca.2009.07.064 |
| format | Article |
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in vivo and
in vitro. When it is coupled to an analytical system, microdialysis can provide near real-time information on the time-dependent concentration changes of analytes in the extracellular space or other aqueous environments. Online systems for the analysis of microdialysis samples enable fast, selective and sensitive analysis while preserving the temporal information. Analytical methods employed for online analysis include liquid chromatography (LC), capillary (CE) and microchip electrophoresis and flow-through biosensor devices. This review article provides an overview of microdialysis sampling and online analysis systems with emphasis on
in vivo analysis. Factors that affect the frequency of analysis and, hence, the temporal resolution of these systems are also discussed.</description><subject>Analytical chemistry</subject><subject>Animals</subject><subject>Applied sciences</subject><subject>Biological and medical sciences</subject><subject>Biosensing Techniques</subject><subject>Biosensors</subject><subject>Biotechnology</subject><subject>Chemistry</subject><subject>Chromatographic methods and physical methods associated with chromatography</subject><subject>Chromatography, High Pressure Liquid</subject><subject>Electrophoresis</subject><subject>Electrophoresis, Capillary</subject><subject>Exact sciences and technology</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>General, instrumentation</subject><subject>Global environmental pollution</subject><subject>In vivo monitoring</subject><subject>Methods. Procedures. 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in vivo and
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Analytical chemistry Animals Applied sciences Biological and medical sciences Biosensing Techniques Biosensors Biotechnology Chemistry Chromatographic methods and physical methods associated with chromatography Chromatography, High Pressure Liquid Electrophoresis Electrophoresis, Capillary Exact sciences and technology Fundamental and applied biological sciences. Psychology General, instrumentation Global environmental pollution In vivo monitoring Methods. Procedures. Technologies Microchip Microchip Analytical Procedures Microdialysis Microdialysis - instrumentation Microdialysis - methods Microdialysis - trends Microfluidics Online Systems - instrumentation Other chromatographic methods Pollution Rats Sensors Various methods and equipments |
| title | Recent trends in microdialysis sampling integrated with conventional and microanalytical systems for monitoring biological events: A review |
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