Paradoxical Association of Enhanced Cholesterol Efflux With Increased Incident Cardiovascular Risks

OBJECTIVE—Diminished cholesterol efflux activity of apolipoprotein B (apoB)–depleted serum is associated with prevalent coronary artery disease, but its prognostic value for incident cardiovascular events is unclear. We investigated the relationship of cholesterol efflux activity with both prevalent...

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Veröffentlicht in:	Arteriosclerosis, thrombosis, and vascular biology thrombosis, and vascular biology, 2013-07, Vol.33 (7), p.1696-1705
Hauptverfasser:	Li, Xin-Min, Tang, Wai Hong Wilson, Mosior, Marian K, Huang, Ying, Wu, Yuping, Matter, William, Gao, Vivian, Schmitt, David, DiDonato, Joseph A, Fisher, Edward A, Smith, Jonathan D, Hazen, Stanley L
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Animals Apolipoprotein A-I - blood Apolipoproteins B - blood ATP Binding Cassette Transporter 1 ATP-Binding Cassette Transporters - metabolism Biomarkers - blood Cardiovascular Diseases - blood Cardiovascular Diseases - epidemiology Cardiovascular Diseases - mortality Case-Control Studies Cell Line Cholesterol - blood Cholesterol, HDL - blood Coronary Angiography Coronary Artery Disease - blood Coronary Artery Disease - epidemiology Female Humans Immunoprecipitation Incidence Logistic Models Macrophages - metabolism Male Mice Middle Aged Multivariate Analysis Myocardial Infarction - blood Myocardial Infarction - epidemiology Ohio - epidemiology Predictive Value of Tests Prognosis Proportional Hazards Models Risk Assessment Risk Factors Serum Albumin - metabolism Serum Albumin, Human Stroke - blood Stroke - epidemiology Time Factors
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