AMP-Activated Protein Kinase α 2 Isoform Suppression in Primary Breast Cancer Alters AMPK Growth Control and Apoptotic Signaling

Adenosine monophosphate-activated protein kinase (AMPK) is a metabolic regulator that promotes energy conservation and restoration when cells are exposed to nutrient stress. Given the high metabolic requirement of cancer cells, AMPK activation has been suggested as a potential preventative and thera...

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Veröffentlicht in:Genes & cancer 2013-01, Vol.4 (1-2), p.3-14
Hauptverfasser: Fox, Melissa M, Phoenix, Kathryn N, Kopsiaftis, Stavros G, Claffey, Kevin P
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Sprache:eng
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