Inactivating Mutations in GT198 in Familial and Early-Onset Breast and Ovarian Cancers

The human GT198 gene (gene symbol PSMC3IP) is located at chromosome 17q21, 470 kb proximal to BRCA1, a locus previously linked to breast and ovarian cancer predisposition. Its protein product (also known as TBPIP and Hop2) has been shown to regulate steroid hormone receptor-mediated gene activation...

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Veröffentlicht in:	Genes & cancer 2013-01, Vol.4 (1-2), p.15-25
Hauptverfasser:	Peng, Min, Bakker, Janine L, Dicioccio, Richard A, Gille, Johan J P, Zhao, Hua, Odunsi, Kunle, Sucheston, Lara, Jaafar, Lahcen, Mivechi, Nahid F, Waisfisz, Quinten, Ko, Lan
Format:	Artikel
Sprache:	eng
Schlagworte:	Original
Online-Zugang:	Volltext
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