Method Development and Analysis of Free HS and HS in Proteoglycans from Pre- and Postmenopausal Women: Evidence for Biosynthetic Pathway Changes in Sulfotransferase and Sulfatase Enzymes

Heparan sulfate (HS) is one of the most complex and informative biopolymers found on the cell surface or in the extracellular matrix as either free HS fragments or constituents of HS proteoglycans (HSPGs). Analysis of free HS and HSPG sugar chains in human serum at the disaccharide level has great p...

Ausführliche Beschreibung