Adrenocortical Carcinoma Is a Lynch Syndrome–Associated Cancer

Adrenocortical carcinoma (ACC) is an endocrine malignancy with a poor prognosis. The association of adult-onset ACC with inherited cancer predisposition syndromes is poorly understood. Our study sought to define the prevalence of Lynch syndrome (LS) among patients with ACC. One hundred fourteen pati...

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Veröffentlicht in:	Journal of clinical oncology 2013-08, Vol.31 (24), p.3012-3018
Hauptverfasser:	RAYMOND, Victoria M, EVERETT, Jessica N, ELSE, Tobias, FURTADO, Larissa V, GUSTAFSON, Shanna L, JUNGBLUTH, Chelsy R, GRUBER, Stephen B, HAMMER, Gary D, STOFFEL, Elena M, GREENSON, Joel K, GIORDANO, Thomas J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Cortex Neoplasms - etiology Adrenal Cortex Neoplasms - genetics Adrenal Cortex Neoplasms - pathology Adrenals. Adrenal axis. Renin-angiotensin system (diseases) Adrenocortical Carcinoma - etiology Adrenocortical Carcinoma - genetics Adrenocortical Carcinoma - pathology Adult Biological and medical sciences Colorectal Neoplasms, Hereditary Nonpolyposis - complications Colorectal Neoplasms, Hereditary Nonpolyposis - genetics Colorectal Neoplasms, Hereditary Nonpolyposis - pathology Endocrinopathies Female Genetic Predisposition to Disease Humans Immunohistochemistry Male Malignant tumors Medical sciences Middle Aged Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Original Reports Prospective Studies Rare Tumors Young Adult
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