Antiglaucomatous effects of the activation of intrinsic Angiotensin-converting enzyme 2

To evaluate the effects of the activation of endogenous angiotensin-converting enzyme 2 (ACE2) using the compound diminazene aceturate (DIZE) in an experimental model of glaucoma in Wistar rats. DIZE (1 mg/kg) was administered daily, either systemically or topically, and the IOP was measured weekly....

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Investigative ophthalmology & visual science 2013-06, Vol.54 (6), p.4296-4306
Hauptverfasser:	Foureaux, Giselle, Nogueira, José C, Nogueira, Bárbara S, Fulgêncio, Gustavo O, Menezes, Gustavo B, Fernandes, Simone O A, Cardoso, Valbert N, Fernandes, Renata S, Oliveira, Gabriel P, Franca, Juçara R, Faraco, André A G, Raizada, Mohan K, Ferreira, Anderson J
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II - analogs & derivatives Angiotensin II - pharmacology Animals Antihypertensive Agents - pharmacology Aqueous Humor - diagnostic imaging Aqueous Humor - secretion Blood Pressure Caspase 3 - metabolism Cell Count Diminazene - analogs & derivatives Diminazene - pharmacology Disease Models, Animal Enzyme Activation - drug effects Fluorescent Antibody Technique, Indirect Glaucoma - enzymology Glaucoma - prevention & control Immunoenzyme Techniques Intraocular Pressure - drug effects Male Nerve Fibers - ultrastructure Ophthalmic Solutions - pharmacology Optic Nerve - ultrastructure Peptide Fragments - pharmacology Peptidyl-Dipeptidase A - metabolism Radionuclide Imaging Rats Rats, Wistar Renin-Angiotensin System - physiology Retina - enzymology Retinal Ganglion Cells - enzymology Retinal Ganglion Cells - pathology Sulfonamides - pharmacology Thiophenes - pharmacology Tonometry, Ocular
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!