A correlation between acute kidney injury and myonecrosis after scheduled percutaneous coronary intervention
Slight elevations in cardiac troponin I and T are frequently observed after percutaneous coronary inter- vention （PCI）. Contrast-induced acute kidney injury （CI-AKI） is a complex syndrome induced by exposure to in- travascular contrast media （CM）. Currently, the relationships between the CM, pre-exi...
Gespeichert in:
| Veröffentlicht in: | Journal of Zhejiang University. B. Science 2013-08, Vol.14 (8), p.713-720 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 720 |
|---|---|
| container_issue | 8 |
| container_start_page | 713 |
| container_title | Journal of Zhejiang University. B. Science |
| container_volume | 14 |
| creator | Zhang, Min Meng, Hao-yu Zhao, Ying-ming Tao, Zhi-wen Gong, Xiao-xuan Wang, Ze-mu Chen, Bo Tao, Zheng-xian Li, Chun-jian Zhu, Tie-bing Wang, Lian-sheng Yang, Zhi-jian |
| description | Slight elevations in cardiac troponin I and T are frequently observed after percutaneous coronary inter- vention （PCI）. Contrast-induced acute kidney injury （CI-AKI） is a complex syndrome induced by exposure to in- travascular contrast media （CM）. Currently, the relationships between the CM, pre-existing kidney insufficiency, CI-AKI and myonecrosis after elective PCI are unclear. To investigate the relationship between CI-AKI and post-procedural myonecrosis （PMN） after PCI, we analyzed 327 non-ST-segment elevation acute coronary syndrome subjects un- dertaking elective PCI. The levels of cardiac troponins （cTns）, cTnl and cTnT, at baseline and on at least one occasion 18-24 h after PCI were measured. We also recorded serum levels of creatinine （SCr） and the urine albumin：creatinine ratio （ACR） before coronary angiography, and 24-48 h and 48-72 h after contrast administration. A post-procedure increase in cTns was detected in 16.21% （53/327） of subjects with cTns levels 〉99th to 5x99th percentile upper ref- erence limit （URL）. Twenty-seven patients （8.26%） developed CI-AKI. CI-AKI occurred more often in subjects with PMN than in those without PMN （20.8% versus 5.8%, respectively, /〉=-0.001）. Multiple logistic regression analysis revealed that pre-existing microalbuminuria （MA） was an important independent predictor of PMN （OR： 3.31; 95% CI： 1.26-8.65, P=0.01）. However, there was no correlation between the incidence of CI-AKI and PMN （OR： 2.38; 95% CI： 0.88-6.46, P=-0.09）. We conclude that pre-existing MA was not only an important independent predictor of CI-AKI but also of PMN. |
| doi_str_mv | 10.1631/jzus.bqicc706 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3735971</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><cqvip_id>46882756</cqvip_id><sourcerecordid>3036317251</sourcerecordid><originalsourceid>FETCH-LOGICAL-c546t-a2e8ec4d073b9e0065f396ce0b54e98c9fd8e11d4998b2d42f3ebfbd8b7082723</originalsourceid><addsrcrecordid>eNp1kUtvEzEUhUcIREthyRYZsZ5gjz1-bJDaiEKlSggJ1pYfd5IJEzuxZ4rCr69HCVFZsLKl-51zj-6pqrcELwin5OPmz5QXdt87JzB_Vl0SyZuaCEmflz8XtCatJBfVq5w3GDOGBX9ZXTRUKiEUvqyGa-RiSjCYsY8BWRh_AwRk3DQC-tX7AAfUh82UDsgEj7aHGMClmPuMTDdCQtmtwU8DeLSDVFQmQJzybBqDSbO4UA8QZvvX1YvODBnenN6r6uft5x_Lr_X9ty93y-v72rWMj7VpQIJjHgtqFWDM244q7gDbloGSTnVeAiGeKSVt41nTUbCd9dIKLBvR0Kvq09F3N9kteFe2JzPoXeq3JZKOptf_TkK_1qv4oKmgrRKkGHw4GaS4nyCPehOnFEpmTRgRbUuUwoWqj9R8kJygO28gWM_l6LkcffP9brks5RT-3dNYZ_pvGwVYHIFcRmEF6cna_zi-PyVYx7DaF83ZlHFZbtFy-ghjSavo</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1417551990</pqid></control><display><type>article</type><title>A correlation between acute kidney injury and myonecrosis after scheduled percutaneous coronary intervention</title><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><creator>Zhang, Min ; Meng, Hao-yu ; Zhao, Ying-ming ; Tao, Zhi-wen ; Gong, Xiao-xuan ; Wang, Ze-mu ; Chen, Bo ; Tao, Zheng-xian ; Li, Chun-jian ; Zhu, Tie-bing ; Wang, Lian-sheng ; Yang, Zhi-jian</creator><creatorcontrib>Zhang, Min ; Meng, Hao-yu ; Zhao, Ying-ming ; Tao, Zhi-wen ; Gong, Xiao-xuan ; Wang, Ze-mu ; Chen, Bo ; Tao, Zheng-xian ; Li, Chun-jian ; Zhu, Tie-bing ; Wang, Lian-sheng ; Yang, Zhi-jian</creatorcontrib><description>Slight elevations in cardiac troponin I and T are frequently observed after percutaneous coronary inter- vention （PCI）. Contrast-induced acute kidney injury （CI-AKI） is a complex syndrome induced by exposure to in- travascular contrast media （CM）. Currently, the relationships between the CM, pre-existing kidney insufficiency, CI-AKI and myonecrosis after elective PCI are unclear. To investigate the relationship between CI-AKI and post-procedural myonecrosis （PMN） after PCI, we analyzed 327 non-ST-segment elevation acute coronary syndrome subjects un- dertaking elective PCI. The levels of cardiac troponins （cTns）, cTnl and cTnT, at baseline and on at least one occasion 18-24 h after PCI were measured. We also recorded serum levels of creatinine （SCr） and the urine albumin：creatinine ratio （ACR） before coronary angiography, and 24-48 h and 48-72 h after contrast administration. A post-procedure increase in cTns was detected in 16.21% （53/327） of subjects with cTns levels 〉99th to 5x99th percentile upper ref- erence limit （URL）. Twenty-seven patients （8.26%） developed CI-AKI. CI-AKI occurred more often in subjects with PMN than in those without PMN （20.8% versus 5.8%, respectively, /〉=-0.001）. Multiple logistic regression analysis revealed that pre-existing microalbuminuria （MA） was an important independent predictor of PMN （OR： 3.31; 95% CI： 1.26-8.65, P=0.01）. However, there was no correlation between the incidence of CI-AKI and PMN （OR： 2.38; 95% CI： 0.88-6.46, P=-0.09）. We conclude that pre-existing MA was not only an important independent predictor of CI-AKI but also of PMN.</description><identifier>ISSN: 1673-1581</identifier><identifier>EISSN: 1862-1783</identifier><identifier>DOI: 10.1631/jzus.bqicc706</identifier><identifier>PMID: 23897790</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Acute Coronary Syndrome - blood ; Acute Coronary Syndrome - complications ; Acute Coronary Syndrome - therapy ; Acute Kidney Injury - blood ; Acute Kidney Injury - etiology ; Acute Kidney Injury - physiopathology ; Aged ; Albuminuria - complications ; Biomedical and Life Sciences ; Biomedicine ; Cardiovascular Clinical Research ; Contrast Media - adverse effects ; Creatinine - blood ; Female ; Humans ; Logistic Models ; Male ; Middle Aged ; Myocardium - pathology ; Necrosis ; Percutaneous Coronary Intervention - adverse effects ; Prospective Studies ; Risk Factors ; Troponin I - blood ; Troponin T - blood ; 临床 ; 冠状动脉 ; 心脏疾病 ; 调查结果</subject><ispartof>Journal of Zhejiang University. B. Science, 2013-08, Vol.14 (8), p.713-720</ispartof><rights>Zhejiang University and Springer-Verlag Berlin Heidelberg 2013</rights><rights>Copyright © Zhejiang University and Springer-Verlag Berlin Heidelberg 2013 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c546t-a2e8ec4d073b9e0065f396ce0b54e98c9fd8e11d4998b2d42f3ebfbd8b7082723</citedby><cites>FETCH-LOGICAL-c546t-a2e8ec4d073b9e0065f396ce0b54e98c9fd8e11d4998b2d42f3ebfbd8b7082723</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/86281A/86281A.jpg</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735971/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735971/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,41464,42533,51294,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23897790$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhang, Min</creatorcontrib><creatorcontrib>Meng, Hao-yu</creatorcontrib><creatorcontrib>Zhao, Ying-ming</creatorcontrib><creatorcontrib>Tao, Zhi-wen</creatorcontrib><creatorcontrib>Gong, Xiao-xuan</creatorcontrib><creatorcontrib>Wang, Ze-mu</creatorcontrib><creatorcontrib>Chen, Bo</creatorcontrib><creatorcontrib>Tao, Zheng-xian</creatorcontrib><creatorcontrib>Li, Chun-jian</creatorcontrib><creatorcontrib>Zhu, Tie-bing</creatorcontrib><creatorcontrib>Wang, Lian-sheng</creatorcontrib><creatorcontrib>Yang, Zhi-jian</creatorcontrib><title>A correlation between acute kidney injury and myonecrosis after scheduled percutaneous coronary intervention</title><title>Journal of Zhejiang University. B. Science</title><addtitle>J. Zhejiang Univ. Sci. B</addtitle><addtitle>Journal of Zhejiang University Science</addtitle><description>Slight elevations in cardiac troponin I and T are frequently observed after percutaneous coronary inter- vention （PCI）. Contrast-induced acute kidney injury （CI-AKI） is a complex syndrome induced by exposure to in- travascular contrast media （CM）. Currently, the relationships between the CM, pre-existing kidney insufficiency, CI-AKI and myonecrosis after elective PCI are unclear. To investigate the relationship between CI-AKI and post-procedural myonecrosis （PMN） after PCI, we analyzed 327 non-ST-segment elevation acute coronary syndrome subjects un- dertaking elective PCI. The levels of cardiac troponins （cTns）, cTnl and cTnT, at baseline and on at least one occasion 18-24 h after PCI were measured. We also recorded serum levels of creatinine （SCr） and the urine albumin：creatinine ratio （ACR） before coronary angiography, and 24-48 h and 48-72 h after contrast administration. A post-procedure increase in cTns was detected in 16.21% （53/327） of subjects with cTns levels 〉99th to 5x99th percentile upper ref- erence limit （URL）. Twenty-seven patients （8.26%） developed CI-AKI. CI-AKI occurred more often in subjects with PMN than in those without PMN （20.8% versus 5.8%, respectively, /〉=-0.001）. Multiple logistic regression analysis revealed that pre-existing microalbuminuria （MA） was an important independent predictor of PMN （OR： 3.31; 95% CI： 1.26-8.65, P=0.01）. However, there was no correlation between the incidence of CI-AKI and PMN （OR： 2.38; 95% CI： 0.88-6.46, P=-0.09）. We conclude that pre-existing MA was not only an important independent predictor of CI-AKI but also of PMN.</description><subject>Acute Coronary Syndrome - blood</subject><subject>Acute Coronary Syndrome - complications</subject><subject>Acute Coronary Syndrome - therapy</subject><subject>Acute Kidney Injury - blood</subject><subject>Acute Kidney Injury - etiology</subject><subject>Acute Kidney Injury - physiopathology</subject><subject>Aged</subject><subject>Albuminuria - complications</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Cardiovascular Clinical Research</subject><subject>Contrast Media - adverse effects</subject><subject>Creatinine - blood</subject><subject>Female</subject><subject>Humans</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Myocardium - pathology</subject><subject>Necrosis</subject><subject>Percutaneous Coronary Intervention - adverse effects</subject><subject>Prospective Studies</subject><subject>Risk Factors</subject><subject>Troponin I - blood</subject><subject>Troponin T - blood</subject><subject>临床</subject><subject>冠状动脉</subject><subject>心脏疾病</subject><subject>调查结果</subject><issn>1673-1581</issn><issn>1862-1783</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kUtvEzEUhUcIREthyRYZsZ5gjz1-bJDaiEKlSggJ1pYfd5IJEzuxZ4rCr69HCVFZsLKl-51zj-6pqrcELwin5OPmz5QXdt87JzB_Vl0SyZuaCEmflz8XtCatJBfVq5w3GDOGBX9ZXTRUKiEUvqyGa-RiSjCYsY8BWRh_AwRk3DQC-tX7AAfUh82UDsgEj7aHGMClmPuMTDdCQtmtwU8DeLSDVFQmQJzybBqDSbO4UA8QZvvX1YvODBnenN6r6uft5x_Lr_X9ty93y-v72rWMj7VpQIJjHgtqFWDM244q7gDbloGSTnVeAiGeKSVt41nTUbCd9dIKLBvR0Kvq09F3N9kteFe2JzPoXeq3JZKOptf_TkK_1qv4oKmgrRKkGHw4GaS4nyCPehOnFEpmTRgRbUuUwoWqj9R8kJygO28gWM_l6LkcffP9brks5RT-3dNYZ_pvGwVYHIFcRmEF6cna_zi-PyVYx7DaF83ZlHFZbtFy-ghjSavo</recordid><startdate>20130801</startdate><enddate>20130801</enddate><creator>Zhang, Min</creator><creator>Meng, Hao-yu</creator><creator>Zhao, Ying-ming</creator><creator>Tao, Zhi-wen</creator><creator>Gong, Xiao-xuan</creator><creator>Wang, Ze-mu</creator><creator>Chen, Bo</creator><creator>Tao, Zheng-xian</creator><creator>Li, Chun-jian</creator><creator>Zhu, Tie-bing</creator><creator>Wang, Lian-sheng</creator><creator>Yang, Zhi-jian</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><general>Zhejiang University Press</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>~WA</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7QP</scope><scope>7TK</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>BKSAR</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>M7S</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PCBAR</scope><scope>PDBOC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>5PM</scope></search><sort><creationdate>20130801</creationdate><title>A correlation between acute kidney injury and myonecrosis after scheduled percutaneous coronary intervention</title><author>Zhang, Min ; Meng, Hao-yu ; Zhao, Ying-ming ; Tao, Zhi-wen ; Gong, Xiao-xuan ; Wang, Ze-mu ; Chen, Bo ; Tao, Zheng-xian ; Li, Chun-jian ; Zhu, Tie-bing ; Wang, Lian-sheng ; Yang, Zhi-jian</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c546t-a2e8ec4d073b9e0065f396ce0b54e98c9fd8e11d4998b2d42f3ebfbd8b7082723</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Acute Coronary Syndrome - blood</topic><topic>Acute Coronary Syndrome - complications</topic><topic>Acute Coronary Syndrome - therapy</topic><topic>Acute Kidney Injury - blood</topic><topic>Acute Kidney Injury - etiology</topic><topic>Acute Kidney Injury - physiopathology</topic><topic>Aged</topic><topic>Albuminuria - complications</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Cardiovascular Clinical Research</topic><topic>Contrast Media - adverse effects</topic><topic>Creatinine - blood</topic><topic>Female</topic><topic>Humans</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Myocardium - pathology</topic><topic>Necrosis</topic><topic>Percutaneous Coronary Intervention - adverse effects</topic><topic>Prospective Studies</topic><topic>Risk Factors</topic><topic>Troponin I - blood</topic><topic>Troponin T - blood</topic><topic>临床</topic><topic>冠状动脉</topic><topic>心脏疾病</topic><topic>调查结果</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhang, Min</creatorcontrib><creatorcontrib>Meng, Hao-yu</creatorcontrib><creatorcontrib>Zhao, Ying-ming</creatorcontrib><creatorcontrib>Tao, Zhi-wen</creatorcontrib><creatorcontrib>Gong, Xiao-xuan</creatorcontrib><creatorcontrib>Wang, Ze-mu</creatorcontrib><creatorcontrib>Chen, Bo</creatorcontrib><creatorcontrib>Tao, Zheng-xian</creatorcontrib><creatorcontrib>Li, Chun-jian</creatorcontrib><creatorcontrib>Zhu, Tie-bing</creatorcontrib><creatorcontrib>Wang, Lian-sheng</creatorcontrib><creatorcontrib>Yang, Zhi-jian</creatorcontrib><collection>中文科技期刊数据库</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>中文科技期刊数据库-7.0平台</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Earth, Atmospheric & Aquatic Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Earth, Atmospheric & Aquatic Science Database</collection><collection>Materials Science Collection</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of Zhejiang University. B. Science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhang, Min</au><au>Meng, Hao-yu</au><au>Zhao, Ying-ming</au><au>Tao, Zhi-wen</au><au>Gong, Xiao-xuan</au><au>Wang, Ze-mu</au><au>Chen, Bo</au><au>Tao, Zheng-xian</au><au>Li, Chun-jian</au><au>Zhu, Tie-bing</au><au>Wang, Lian-sheng</au><au>Yang, Zhi-jian</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A correlation between acute kidney injury and myonecrosis after scheduled percutaneous coronary intervention</atitle><jtitle>Journal of Zhejiang University. B. Science</jtitle><stitle>J. Zhejiang Univ. Sci. B</stitle><addtitle>Journal of Zhejiang University Science</addtitle><date>2013-08-01</date><risdate>2013</risdate><volume>14</volume><issue>8</issue><spage>713</spage><epage>720</epage><pages>713-720</pages><issn>1673-1581</issn><eissn>1862-1783</eissn><abstract>Slight elevations in cardiac troponin I and T are frequently observed after percutaneous coronary inter- vention （PCI）. Contrast-induced acute kidney injury （CI-AKI） is a complex syndrome induced by exposure to in- travascular contrast media （CM）. Currently, the relationships between the CM, pre-existing kidney insufficiency, CI-AKI and myonecrosis after elective PCI are unclear. To investigate the relationship between CI-AKI and post-procedural myonecrosis （PMN） after PCI, we analyzed 327 non-ST-segment elevation acute coronary syndrome subjects un- dertaking elective PCI. The levels of cardiac troponins （cTns）, cTnl and cTnT, at baseline and on at least one occasion 18-24 h after PCI were measured. We also recorded serum levels of creatinine （SCr） and the urine albumin：creatinine ratio （ACR） before coronary angiography, and 24-48 h and 48-72 h after contrast administration. A post-procedure increase in cTns was detected in 16.21% （53/327） of subjects with cTns levels 〉99th to 5x99th percentile upper ref- erence limit （URL）. Twenty-seven patients （8.26%） developed CI-AKI. CI-AKI occurred more often in subjects with PMN than in those without PMN （20.8% versus 5.8%, respectively, /〉=-0.001）. Multiple logistic regression analysis revealed that pre-existing microalbuminuria （MA） was an important independent predictor of PMN （OR： 3.31; 95% CI： 1.26-8.65, P=0.01）. However, there was no correlation between the incidence of CI-AKI and PMN （OR： 2.38; 95% CI： 0.88-6.46, P=-0.09）. We conclude that pre-existing MA was not only an important independent predictor of CI-AKI but also of PMN.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>23897790</pmid><doi>10.1631/jzus.bqicc706</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1673-1581 |
| ispartof | Journal of Zhejiang University. B. Science, 2013-08, Vol.14 (8), p.713-720 |
| issn | 1673-1581 1862-1783 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3735971 |
| source | MEDLINE; Springer Nature - Complete Springer Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Acute Coronary Syndrome - blood Acute Coronary Syndrome - complications Acute Coronary Syndrome - therapy Acute Kidney Injury - blood Acute Kidney Injury - etiology Acute Kidney Injury - physiopathology Aged Albuminuria - complications Biomedical and Life Sciences Biomedicine Cardiovascular Clinical Research Contrast Media - adverse effects Creatinine - blood Female Humans Logistic Models Male Middle Aged Myocardium - pathology Necrosis Percutaneous Coronary Intervention - adverse effects Prospective Studies Risk Factors Troponin I - blood Troponin T - blood 临床 冠状动脉 心脏疾病 调查结果 |
| title | A correlation between acute kidney injury and myonecrosis after scheduled percutaneous coronary intervention |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-10T00%3A09%3A14IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20correlation%20between%20acute%20kidney%20injury%20and%20myonecrosis%20after%20scheduled%20percutaneous%20coronary%20intervention&rft.jtitle=Journal%20of%20Zhejiang%20University.%20B.%20Science&rft.au=Zhang,%20Min&rft.date=2013-08-01&rft.volume=14&rft.issue=8&rft.spage=713&rft.epage=720&rft.pages=713-720&rft.issn=1673-1581&rft.eissn=1862-1783&rft_id=info:doi/10.1631/jzus.bqicc706&rft_dat=%3Cproquest_pubme%3E3036317251%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1417551990&rft_id=info:pmid/23897790&rft_cqvip_id=46882756&rfr_iscdi=true |