HIV-associated chronic immune activation

Summary Systemic chronic immune activation is considered today as the driving force of CD4+ T‐cell depletion and acquired immunodeficiency syndrome (AIDS). A residual chronic immune activation persists even in HIV‐infected patients in which viral replication is successfully inhibited by anti‐retrovi...

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Veröffentlicht in:	Immunological reviews 2013-07, Vol.254 (1), p.78-101
Hauptverfasser:	Paiardini, Mirko, Müller-Trutwin, Michaela
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CD4-Positive T-Lymphocytes - immunology CD4-Positive T-Lymphocytes - virology HIV HIV Infections - immunology HIV Infections - virology HIV-1 - immunology HIV-1 - metabolism Human immunodeficiency virus Humans immune activation Immunology inflammation Life Sciences Lymphocyte Activation - immunology Lymphocyte Depletion Lymphoid Tissue - immunology Lymphoid Tissue - virology Microbiology and Parasitology natural hosts pathogenesis Simian Acquired Immunodeficiency Syndrome - immunology Simian Acquired Immunodeficiency Syndrome - virology SIV Viral Proteins - immunology Virology Virus Replication
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