Uveal melanoma: Ocular and systemic disease
Although rare, uveal melanoma is the most common intraocular tumor in adults. Most cases arise from the choroidal layer of the uvea, displaying a discoid, collar-button, or mushroom shaped growth. Histopathologically, neoplasms are classified by the dominant cell type: spindle, epithelioid or mixed...
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| Veröffentlicht in: | Saudi journal of ophthalmology 2012-04, Vol.26 (2), p.145-149 |
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| container_title | Saudi journal of ophthalmology |
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| creator | Miyamoto, Cristina Balazsi, Matthew Bakalian, Silvin Fernandes, Bruno F. Burnier, Miguel N. |
| description | Although rare, uveal melanoma is the most common intraocular tumor in adults. Most cases arise from the choroidal layer of the uvea, displaying a discoid, collar-button, or mushroom shaped growth. Histopathologically, neoplasms are classified by the dominant cell type: spindle, epithelioid or mixed spindle cell type. The most important prognostic factors are cell type, nucleolar size, largest tumor dimension, and mitotic figures. Patient prognosis is poor when metastases occur in the liver, one of the main reasons that despite advances in the diagnosis and treatment of uveal melanoma, the mortality rate has not change significantly since 1973. |
| doi_str_mv | 10.1016/j.sjopt.2012.02.010 |
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| source | Access via ScienceDirect (Elsevier); EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Cancer Choroidal Metastasis Ophthalmic Pathology Update Uveal melanoma |
| title | Uveal melanoma: Ocular and systemic disease |
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