The Tumor Suppressor Rb Critically Regulates Starvation-Induced Stress Response in C. elegans

How animals coordinate gene expression in response to starvation is an outstanding problem closely linked to aging, obesity, and cancer [1–5]. Newly hatched Caenorhabditis elegans respond to food deprivation by halting development and promoting long-term survival (L1 diapause), thereby providing an...

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Veröffentlicht in:	Current biology 2013-06, Vol.23 (11), p.975-980
Hauptverfasser:	Cui, Mingxue, Cohen, Max L., Teng, Cindy, Han, Min
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals antagonists Caenorhabditis elegans Caenorhabditis elegans - genetics Caenorhabditis elegans - physiology Caenorhabditis elegans Proteins - genetics Caenorhabditis elegans Proteins - metabolism diapause electron transport chain Food Deprivation gene expression Gene Expression Regulation genes Genes, Tumor Suppressor Insulin - genetics Insulin - metabolism Insulin-Like Growth Factor I - genetics Insulin-Like Growth Factor I - metabolism Molecular Sequence Data neurons obesity Repressor Proteins - genetics Repressor Proteins - metabolism Signal Transduction starvation stress response Stress, Physiological transcriptome
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