Stretch injury selectively enhances extrasynaptic, GluN2B-containing NMDA receptor function in cortical neurons

Alterations in the function and expression of NMDA receptors are observed after in vivo and in vitro traumatic brain injury. We recently reported that mechanical stretch injury in cortical neurons transiently increases the contribution of NMDA receptors to network activity and results in an increase...

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Veröffentlicht in:	Journal of neurophysiology 2013-07, Vol.110 (1), p.131-140
Hauptverfasser:	Ferrario, Carrie R, Ndukwe, Blaise O, Ren, Jianhua, Satin, Leslie S, Goforth, Paulette B
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cells, Cultured Cerebral Cortex - physiology Neurons - physiology Rats Rats, Sprague-Dawley Receptors, AMPA - metabolism Receptors, N-Methyl-D-Aspartate - metabolism Stress, Mechanical
Online-Zugang:	Volltext
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