LRP-1: A Checkpoint for the Extracellular Matrix Proteolysis

Low-density lipoprotein receptor-related protein-(LRP-1) is a large endocytic receptor that binds more than 35 ligands and exhibits signaling properties. Proteinases capable of degrading extracellular matrix (ECM), called matrix proteinases in this paper, are mainly serine proteinases: the activator...

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Veröffentlicht in:	BioMed research international 2013-01, Vol.2013 (2013), p.1-7
Hauptverfasser:	Emonard, Hervé, Dedieu, Stéphane, Verzeaux, Laurie, Etique, Nicolas
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Cell adhesion & migration Cell receptors Endocytosis Enzymes Extracellular Matrix Humans Ligands Low Density Lipoprotein Receptor-Related Protein-1 - metabolism Low density lipoproteins Physiological aspects Protein Binding Proteolysis Review Signal Transduction Tissue Plasminogen Activator - metabolism Urokinase-Type Plasminogen Activator - metabolism Wound healing
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