The role of Drosophila cytidine monophosphate-sialic acid synthetase in the nervous system

While sialylation plays important functions in the nervous system, the complexity of glycosylation pathways and limitations of genetic approaches preclude the efficient analysis of these functions in mammalian organisms. Drosophila has recently emerged as a promising model for studying neural sialyl...

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Veröffentlicht in:	The Journal of neuroscience 2013-07, Vol.33 (30), p.12306-12315
Hauptverfasser:	Islam, Rafique, Nakamura, Michiko, Scott, Hilary, Repnikova, Elena, Carnahan, Mindy, Pandey, Dheeraj, Caster, Courtney, Khan, Saba, Zimmermann, Tina, Zoran, Mark J, Panin, Vladislav M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Genetically Modified Cytidine Monophosphate - metabolism Drosophila Drosophila - enzymology Drosophila - genetics Drosophila Proteins - genetics Drosophila Proteins - metabolism Evolution, Molecular Gene Expression Regulation, Developmental - physiology Ligases - genetics Ligases - metabolism Longevity - genetics Metazoa N-Acetylneuraminic Acid - metabolism N-Acylneuraminate Cytidylyltransferase - genetics N-Acylneuraminate Cytidylyltransferase - metabolism Nervous System Physiological Phenomena - genetics Neuromuscular Junction - genetics Neuromuscular Junction - metabolism Paralysis - genetics Paralysis - metabolism Secretory Vesicles - physiology Sialyltransferases - genetics Sialyltransferases - metabolism Synaptic Transmission - genetics Synaptic Transmission - physiology Temperature
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