CEP120 interacts with CPAP and positively regulates centriole elongation

Centriole duplication begins with the formation of a single procentriole next to a preexisting centriole. CPAP (centrosomal protein 4.1-associated protein) was previously reported to participate in centriole elongation. Here, we show that CEP120 is a cell cycle-regulated protein that directly intera...

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Veröffentlicht in:	The Journal of cell biology 2013-07, Vol.202 (2), p.211-219
Hauptverfasser:	Lin, Yi-Nan, Wu, Chien-Ting, Lin, Yu-Chih, Hsu, Wen-Bin, Tang, Chieh-Ju C, Chang, Ching-Wen, Tang, Tang K
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Autoradiography Binding sites Cell cycle Cell Cycle Proteins - genetics Cell Cycle Proteins - metabolism Centrioles - genetics Centrioles - metabolism Green Fluorescent Proteins - genetics Green Fluorescent Proteins - metabolism HEK293 Cells HeLa Cells Humans Intracellular Signaling Peptides and Proteins - genetics Intracellular Signaling Peptides and Proteins - metabolism Microtubule-Associated Proteins - genetics Microtubule-Associated Proteins - metabolism Mutation Protein Binding Protein Interaction Mapping Protein Multimerization Protein Structure, Tertiary Proteins RNA, Small Interfering - genetics RNA, Small Interfering - metabolism S Phase Cell Cycle Checkpoints Transfection
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