Presynaptic CaV1.3 channels regulate synaptic ribbon size and are required for synaptic maintenance in sensory hair cells

L-type calcium channels (Ca(V)1) are involved in diverse processes, such as neurotransmission, hormone secretion, muscle contraction, and gene expression. In this study, we uncover a role for Ca(V)1.3a in regulating the architecture of a cellular structure, the ribbon synapse, in developing zebrafis...

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Veröffentlicht in:	The Journal of neuroscience 2012-11, Vol.32 (48), p.17273-17286
Hauptverfasser:	Sheets, Lavinia, Kindt, Katie S, Nicolson, Teresa
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium Channels, L-Type - genetics Calcium Channels, L-Type - metabolism Danio rerio Freshwater Hair Cells, Auditory - cytology Hair Cells, Auditory - metabolism Synapses - genetics Synapses - metabolism Synaptic Transmission - physiology Synaptic Vesicles - genetics Synaptic Vesicles - metabolism Zebrafish - metabolism Zebrafish Proteins
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