Effects of Disturbed Flow on Endothelial Cells

Vascular endothelial cells (ECs) play significant roles in regulating circulatory functions. The shear stress resulting from blood flow modulates EC functions by activating mechano-sensors, signaling pathways, and gene and protein expressions. Shear stress with a clear direction resulting form pulsa...

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Veröffentlicht in:	Annals of biomedical engineering 2008-04, Vol.36 (4), p.554-562
1. Verfasser:	Chien, Shu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry Biological and Medical Physics Biomechanics Biomedical and Life Sciences Biomedical Engineering and Bioengineering Biomedicine Biophysics Blood Flow Velocity - physiology Blood Pressure - physiology Classical Mechanics Computer Simulation Endothelial Cells - physiology Humans Mechanotransduction, Cellular - physiology Models, Cardiovascular Shear Strength Shear stress
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