Novelty and anxiolytic drugs dissociate two components of hippocampal theta in behaving rats

Hippocampal processing is strongly implicated in both spatial cognition and anxiety and is temporally organized by the theta rhythm. However, there has been little attempt to understand how each type of processing relates to the other in behaving animals, despite their common substrate. In freely mo...

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Veröffentlicht in:	The Journal of neuroscience 2013-05, Vol.33 (20), p.8650-8667
Hauptverfasser:	Wells, Christine E, Amos, Doran P, Jeewajee, Ali, Douchamps, Vincent, Rodgers, John, O'Keefe, John, Burgess, Neil, Lever, Colin
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Animals Anti-Anxiety Agents - pharmacology Anxiety - drug therapy Anxiety - etiology Body Temperature - drug effects Disease Models, Animal Dose-Response Relationship, Drug Electroencephalography Evoked Potentials - drug effects Exploratory Behavior - drug effects Exploratory Behavior - physiology Hippocampus - drug effects Hippocampus - physiology Male Rats Space Perception - drug effects Space Perception - physiology Theta Rhythm - drug effects Theta Rhythm - physiology Time Factors Wakefulness - drug effects Wakefulness - physiology
Online-Zugang:	Volltext
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