Serum antibodies to periodontal pathogens are a risk factor for Alzheimer’s disease

Abstract Background Chronic inflammation in periodontal disease has been suggested as a potential risk factor in Alzheimer’s disease (AD). The purpose of this study was to examine serum antibody levels to bacteria of periodontal disease in participants who eventually converted to AD compared with th...

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Veröffentlicht in:	Alzheimer's & dementia 2012-05, Vol.8 (3), p.196-203
Hauptverfasser:	Sparks Stein, Pamela, Steffen, Michelle J, Smith, Charles, Jicha, Gregory, Ebersole, Jeffrey L, Abner, Erin, Dawson, Dolph
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Alzheimer Disease - blood Alzheimer Disease - microbiology Alzheimer's disease Antibodies Antibodies, Bacterial - blood Antibody Apolipoproteins E - genetics Bacteria Bacteroidaceae Infections - blood Bacteroidaceae Infections - complications Bacteroidaceae Infections - immunology Cognitive Dysfunction - blood Cognitive Dysfunction - microbiology Conversion Disease Progression Enzyme-Linked Immunosorbent Assay Female Humans Immunoglobulin G - blood Longitudinal Studies Male Mental Status Schedule Middle Aged Mild cognitive impairment Neurology Periodontal bacteria Periodontal disease Periodontitis Porphyromonas gingivalis - immunology Prevotella intermedia - immunology Retrospective Studies Risk Factors Serum
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