Human Pancreatic β-Cell G1/S Molecule Cell Cycle Atlas

Expansion of pancreatic β-cells is a key goal of diabetes research, yet induction of adult human β-cell replication has proven frustratingly difficult. In part, this reflects a lack of understanding of cell cycle control in the human β-cell. Here, we provide a comprehensive immunocytochemical "...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2013-07, Vol.62 (7), p.2450-2459
Hauptverfasser:	FIASCHI-TAESCH, Nathalie M, KLEINBERGER, Jeffrey W, STEWART, Andrew F, SALIM, Fatimah G, TROXELL, Ronnie, WILLS, Rachel, TANWIR, Mansoor, CASINELLI, Gabriella, COX, Amy E, TAKANE, Karen K, SCOTT, Donald K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biological and medical sciences Cell cycle Cell Cycle - physiology Cell Nucleus - metabolism Cell Proliferation Child Cyclin-Dependent Kinases - metabolism Cyclins - metabolism Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Genetic aspects Humans Insulin-Secreting Cells - cytology Insulin-Secreting Cells - metabolism Insulin-Secreting Cells - physiology Medical sciences Middle Aged Original Research Pancreatic beta cells Physiological aspects Subcellular Fractions
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