Pancreatic Beta Cell Mass PET Imaging and Quantification with [11C]DTBZ and [18F]FP-(+)-DTBZ in Rodent Models of Diabetes

Purpose The aim of this study is to compare the utility of two positron emission tomography (PET) imaging ligands ((+)-[ 11 C]dihydrotetrabenazine ([ 11 C]DTBZ) and the fluoropropyl analog ([ 18 F]FP-(+)-DTBZ)) that target islet β-cell vesicular monoamine transporter type II to measure pancreatic β-...

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