Sexual dimorphism: the aging kidney, involvement of nitric oxide deficiency, and angiotensin II overactivity

Females develop less age-dependent loss of renal function, which may be in part due to cardiorenal protective effects of estrogens. The impact of androgen level on cardiovascular-renal health is controversial. Estrogen acts through multiple mechanisms, sometimes beneficial, sometimes damaging, which...

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Veröffentlicht in:	The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 2012-12, Vol.67 (12), p.1365-1372
1. Verfasser:	Baylis, Chris
Format:	Artikel
Sprache:	eng
Schlagworte:	ACE inhibitors Aged Aging - physiology Androgens - physiology Angiotensin II - physiology Animals Cardiovascular disease Estrogens Female Glomerular Filtration Rate - physiology Humans Kidney diseases Kidney Glomerulus - physiology Male Nitric oxide Nitric Oxide - deficiency Oxidative Stress - physiology Review Sex Characteristics Womens health
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