Redox Proteomics Uncovers Peroxynitrite-sensitive Proteins That Help Escherichia coli to Overcome Nitrosative Stress

Peroxynitrite is a highly reactive chemical species with antibacterial properties that are synthesized in immune cells. In a proteomic approach, we identified specific target proteins of peroxynitrite-induced modifications in Escherichia coli. Although peroxynitrite caused a fairly indiscriminate ni...

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Veröffentlicht in:	The Journal of biological chemistry 2013-07, Vol.288 (27), p.19698-19714
Hauptverfasser:	Lindemann, Claudia, Lupilova, Nataliya, Müller, Alexandra, Warscheid, Bettina, Meyer, Helmut E., Kuhlmann, Katja, Eisenacher, Martin, Leichert, Lars I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Escherichia coli - chemistry Escherichia coli - genetics Escherichia coli - metabolism Escherichia coli Proteins - chemistry Escherichia coli Proteins - genetics Escherichia coli Proteins - metabolism Genomics and Proteomics Microbiology Nitrosative Stress Oxidation-Reduction Oxidative Stress - drug effects Oxidative Stress - genetics Peroxynitrite Peroxynitrous Acid - chemistry Peroxynitrous Acid - pharmacology Proteomics Redox Thiol
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