An in vivo and in vitro study of the mechanism of prednisone-induced insulin resistance in healthy subjects

Prednisone-induced insulin resistance may depend on either reduced sensitivity (receptor defect) or reduced response to insulin (postreceptor defect). To clarify the mechanism of prednisone-induced insulin resistance, a [3H]glucose infusion (1 microCi/min) was performed for 120 min before and during...

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Veröffentlicht in:	The Journal of clinical investigation 1983-11, Vol.72 (5), p.1814-1820
Hauptverfasser:	PAGANO, G, CAVALLO-PERIN, P, CASSADER, M, BRUNO, A, OZZELLO, A, MASCIOLA, P, DALL'OMO, A. M, IMBIMBO, B
Format:	Artikel
Sprache:	eng
Schlagworte:	3-O-Methylglucose Adipose Tissue - metabolism Adult Biological and medical sciences Blood Glucose - metabolism Female Glucose Hormones. Endocrine system Humans Insulin - blood Insulin Resistance Male Medical sciences Metabolic Clearance Rate Methylglucosides - metabolism Middle Aged Pharmacology. Drug treatments Prednisone - adverse effects Receptor, Insulin - metabolism
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