CYP1A1, GSTM1, GSTT1 and NQO1 polymorphisms and colorectal adenomas in Japanese men

To investigate the role of functional genetic polymorphisms of metabolic enzymes of tobacco carcinogens in the development of colorectal adenomas. The study subjects were 455 patients with colorectal adenomas and 1052 controls with no polyps who underwent total colonoscopy in a preretirement health...

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Veröffentlicht in:	World journal of gastroenterology : WJG 2013-07, Vol.19 (25), p.4023-4030
Hauptverfasser:	Hamachi, Tadamichi, Tajima, Osamu, Uezono, Kousaku, Tabata, Shinji, Abe, Hiroshi, Ohnaka, Keizo, Kono, Suminori
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoma - epidemiology Adenoma - ethnology Adenoma - genetics Alleles Asian Continental Ancestry Group - ethnology Asian Continental Ancestry Group - genetics Brief Case-Control Studies Colorectal Neoplasms - epidemiology Colorectal Neoplasms - ethnology Colorectal Neoplasms - genetics Cytochrome P-450 CYP1A1 - genetics Genetic Predisposition to Disease - epidemiology Genetic Predisposition to Disease - ethnology Genetic Predisposition to Disease - genetics Genotype Glutathione Transferase - genetics Humans Japan - epidemiology Life Style Male Middle Aged NAD(P)H Dehydrogenase (Quinone) - genetics Polymorphism, Genetic - genetics Risk Factors Smoking - adverse effects Surveys and Questionnaires
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