Bleomycin-induced flagellate dermatitis
Flagellate dermatitis shows very characteristic lesions: linear erythema or hyperpigmentation in various areas of the skin. It is a side effect of bleomycin, an immunosupressive drug used for several types of cancers. All physicians must be aware of this disease so they can make a rapid diagnosis an...
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Veröffentlicht in: | BMJ case reports 2013-06, Vol.2013, p.bcr2013009764 |
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creator | Grynszpan, Rachel Niemeyer-Corbellini, João Paulo Lopes, Marien Siqueira Soto Ramos-e-Silva, Marcia |
description | Flagellate dermatitis shows very characteristic lesions: linear erythema or hyperpigmentation in various areas of the skin. It is a side effect of bleomycin, an immunosupressive drug used for several types of cancers. All physicians must be aware of this disease so they can make a rapid diagnosis and interrupt the causative agent. Our patient presented during chemotherapy for a Hodgkin's lymphoma pruritic, erythematous lesions on the lower limbs and the back diagnosed as flagellate dermatitis due to bleomycin. |
doi_str_mv | 10.1136/bcr-2013-009764 |
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It is a side effect of bleomycin, an immunosupressive drug used for several types of cancers. All physicians must be aware of this disease so they can make a rapid diagnosis and interrupt the causative agent. Our patient presented during chemotherapy for a Hodgkin's lymphoma pruritic, erythematous lesions on the lower limbs and the back diagnosed as flagellate dermatitis due to bleomycin.</description><identifier>ISSN: 1757-790X</identifier><identifier>EISSN: 1757-790X</identifier><identifier>DOI: 10.1136/bcr-2013-009764</identifier><identifier>PMID: 23814202</identifier><language>eng</language><publisher>England: BMJ Publishing Group LTD</publisher><subject>Adult ; Antibiotics ; Antibiotics, Antineoplastic - adverse effects ; Bleomycin - adverse effects ; Dermatitis ; Drug dosages ; Drug Eruptions - etiology ; Drug Eruptions - pathology ; Erythema ; Female ; Hodgkin Disease - drug therapy ; Humans ; Hyperpigmentation - etiology ; Hyperpigmentation - pathology ; Other ; Patients ; Skin ; South/Central America ; Toxicity ; Unexpected Outcome (Positive or Negative) Including Adverse Drug Reactions</subject><ispartof>BMJ case reports, 2013-06, Vol.2013, p.bcr2013009764</ispartof><rights>2013 BMJ Publishing Group Ltd</rights><rights>Copyright: 2013 2013 BMJ Publishing Group Ltd</rights><rights>2013 BMJ Publishing Group Ltd 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b4414-40292c8f6d85b7b95585b01172e70a1562d917cb1f4949a964893f02846b24ab3</citedby><cites>FETCH-LOGICAL-b4414-40292c8f6d85b7b95585b01172e70a1562d917cb1f4949a964893f02846b24ab3</cites><orcidid>0000-0003-1625-0760</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702947/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702947/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23814202$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Grynszpan, Rachel</creatorcontrib><creatorcontrib>Niemeyer-Corbellini, João Paulo</creatorcontrib><creatorcontrib>Lopes, Marien Siqueira Soto</creatorcontrib><creatorcontrib>Ramos-e-Silva, Marcia</creatorcontrib><title>Bleomycin-induced flagellate dermatitis</title><title>BMJ case reports</title><addtitle>BMJ Case Rep</addtitle><description>Flagellate dermatitis shows very characteristic lesions: linear erythema or hyperpigmentation in various areas of the skin. It is a side effect of bleomycin, an immunosupressive drug used for several types of cancers. All physicians must be aware of this disease so they can make a rapid diagnosis and interrupt the causative agent. Our patient presented during chemotherapy for a Hodgkin's lymphoma pruritic, erythematous lesions on the lower limbs and the back diagnosed as flagellate dermatitis due to bleomycin.</description><subject>Adult</subject><subject>Antibiotics</subject><subject>Antibiotics, Antineoplastic - adverse effects</subject><subject>Bleomycin - adverse effects</subject><subject>Dermatitis</subject><subject>Drug dosages</subject><subject>Drug Eruptions - etiology</subject><subject>Drug Eruptions - pathology</subject><subject>Erythema</subject><subject>Female</subject><subject>Hodgkin Disease - drug therapy</subject><subject>Humans</subject><subject>Hyperpigmentation - etiology</subject><subject>Hyperpigmentation - pathology</subject><subject>Other</subject><subject>Patients</subject><subject>Skin</subject><subject>South/Central America</subject><subject>Toxicity</subject><subject>Unexpected Outcome (Positive or Negative) Including Adverse Drug Reactions</subject><issn>1757-790X</issn><issn>1757-790X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkE1LAzEQhoMottSevUnBgyCszSTZzeYiaPELCl4UvIUkm6277EdNdoX-e1O2lnoylwnMM-8MD0LngG8AaDLXxkUEA40wFjxhR2gMPOYRF_jj-OA_QlPvSxweBZYyeopGhKbACCZjdHVf2bbemKKJiibrjc1meaVWtqpUZ2eZdbXqiq7wZ-gkV5W3012doPfHh7fFc7R8fXpZ3C0jzRiwiGEiiEnzJEtjzbWI41AxACeWYwVxQjIB3GjImWBCiYSlguaYpCzRhClNJ-h2yF33uraZsU3nVCXXrqiV28hWFfJvpyk-5ar9lpSH1YyHgMtdgGu_eus7Wba9a8LNEnhKSQIxhUDNB8q41ntn8_0GwHIrVwa5citXDnLDxMXhYXv-V2UArgdA1-W_aT_zgoB0</recordid><startdate>20130627</startdate><enddate>20130627</enddate><creator>Grynszpan, Rachel</creator><creator>Niemeyer-Corbellini, João Paulo</creator><creator>Lopes, Marien Siqueira Soto</creator><creator>Ramos-e-Silva, Marcia</creator><general>BMJ Publishing Group LTD</general><general>BMJ Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-1625-0760</orcidid></search><sort><creationdate>20130627</creationdate><title>Bleomycin-induced flagellate dermatitis</title><author>Grynszpan, Rachel ; Niemeyer-Corbellini, João Paulo ; Lopes, Marien Siqueira Soto ; Ramos-e-Silva, Marcia</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b4414-40292c8f6d85b7b95585b01172e70a1562d917cb1f4949a964893f02846b24ab3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adult</topic><topic>Antibiotics</topic><topic>Antibiotics, Antineoplastic - adverse effects</topic><topic>Bleomycin - adverse effects</topic><topic>Dermatitis</topic><topic>Drug dosages</topic><topic>Drug Eruptions - etiology</topic><topic>Drug Eruptions - pathology</topic><topic>Erythema</topic><topic>Female</topic><topic>Hodgkin Disease - drug therapy</topic><topic>Humans</topic><topic>Hyperpigmentation - etiology</topic><topic>Hyperpigmentation - pathology</topic><topic>Other</topic><topic>Patients</topic><topic>Skin</topic><topic>South/Central America</topic><topic>Toxicity</topic><topic>Unexpected Outcome (Positive or Negative) Including Adverse Drug Reactions</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Grynszpan, Rachel</creatorcontrib><creatorcontrib>Niemeyer-Corbellini, João Paulo</creatorcontrib><creatorcontrib>Lopes, Marien Siqueira Soto</creatorcontrib><creatorcontrib>Ramos-e-Silva, Marcia</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BMJ case reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Grynszpan, Rachel</au><au>Niemeyer-Corbellini, João Paulo</au><au>Lopes, Marien Siqueira Soto</au><au>Ramos-e-Silva, Marcia</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Bleomycin-induced flagellate dermatitis</atitle><jtitle>BMJ case reports</jtitle><addtitle>BMJ Case Rep</addtitle><date>2013-06-27</date><risdate>2013</risdate><volume>2013</volume><spage>bcr2013009764</spage><pages>bcr2013009764-</pages><issn>1757-790X</issn><eissn>1757-790X</eissn><abstract>Flagellate dermatitis shows very characteristic lesions: linear erythema or hyperpigmentation in various areas of the skin. It is a side effect of bleomycin, an immunosupressive drug used for several types of cancers. All physicians must be aware of this disease so they can make a rapid diagnosis and interrupt the causative agent. Our patient presented during chemotherapy for a Hodgkin's lymphoma pruritic, erythematous lesions on the lower limbs and the back diagnosed as flagellate dermatitis due to bleomycin.</abstract><cop>England</cop><pub>BMJ Publishing Group LTD</pub><pmid>23814202</pmid><doi>10.1136/bcr-2013-009764</doi><orcidid>https://orcid.org/0000-0003-1625-0760</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Adult Antibiotics Antibiotics, Antineoplastic - adverse effects Bleomycin - adverse effects Dermatitis Drug dosages Drug Eruptions - etiology Drug Eruptions - pathology Erythema Female Hodgkin Disease - drug therapy Humans Hyperpigmentation - etiology Hyperpigmentation - pathology Other Patients Skin South/Central America Toxicity Unexpected Outcome (Positive or Negative) Including Adverse Drug Reactions |
title | Bleomycin-induced flagellate dermatitis |
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